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Comment
. 2021 Jan:146:110464.
doi: 10.1016/j.mehy.2020.110464. Epub 2020 Dec 22.

Closing the portal to SARS-CoV-2 cellular entry: May open newer avenues…

Affiliations
Comment

Closing the portal to SARS-CoV-2 cellular entry: May open newer avenues…

Ridhima Sharma et al. Med Hypotheses. 2021 Jan.
No abstract available

Keywords: COVID-19; Camostat mesylate; Cellular entry; Nafamostat mesylate; SARS-CoV-2 pneumonia; Thrombosis; Transmembrane protease serine 2 (TMPRSS2).

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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References

    1. Kumar A., Narayan R.K., Kumari C., Faiq M.A., Kulandhasamy M., Kant K., Pareek V. SARS-CoV-2 cell entry receptor ACE2 mediated endothelial dysfunction leads to vascular thrombosis in COVID-19 patients. Med Hypotheses. 2020;145:110320. doi: 10.1016/j.mehy.2020.110320. - DOI - PMC - PubMed
    1. Magoon R., ItiShri, Kohli J.K., Kashav R. Inhaled milrinone for sick COVID-19 cohort: a pathophysiology driven hypothesis! Med Hypotheses. 2020:110441. doi: 10.1016/j.mehy.2020.110441. - DOI - PMC - PubMed
    1. Hofmann-Winkler H., Moerer O., Alt-Epping S., Bräuer A., Büttner B., Müller M. Camostat mesylate may reduce severity of Coronavirus disease 2019 sepsis: a first observation. Crit Care Explor. 2020;2(11):e0284. doi: 10.1097/CCE.0000000000000284. - DOI - PMC - PubMed
    1. Breining P., Frølund A.L., Højen J.F., Gunst J.D., Staerke N.B., Saedder E. Camostat mesylate against SARS‐CoV‐2 and COVID‐19—rationale, dosing and safety. Clin Pharmacol Toxicol. 2020 doi: 10.1111/bcpt.13533. - DOI - PubMed
    1. Asakura H., Ogawa H. Potential of heparin and nafamostat combination therapy for COVID‐19. J Thromb Haemost. 2020;18(6):1521–1522. doi: 10.1111/jth.14858. - DOI - PMC - PubMed

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