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. 2020 Dec 24;10(1):22384.
doi: 10.1038/s41598-020-79468-8.

First detection of bat-borne Issyk-Kul virus in Europe

Annika Brinkmann  1 , Claudia Kohl  2 , Aleksandar Radonić  3 , Piotr Wojtek Dabrowski  4 , Kristin Mühldorfer  5 , Andreas Nitsche  1 , Gudrun Wibbelt  5 , Andreas Kurth  1
Affiliations

First detection of bat-borne Issyk-Kul virus in Europe

Annika Brinkmann et al. Sci Rep. .

Abstract

Bats have been gaining attention as potential reservoir hosts of numerous viruses pathogenic to animals and man. Issyk-Kul virus, a member of the family Nairoviridae, was first isolated in the 1970s from vespertilionid bats in Central Asia. Issyk-Kul virus has been described as human-pathogenic virus, causing febrile outbreaks in humans with headaches, myalgia and nausea. Here we describe the detection of a novel strain of Issyk-Kul virus from Eptesicus nilssonii in Germany. This finding indicates for the first time the prevalence of these zoonotic viruses in Europe.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Protein alignment and secondary structure prediction of the nucleoprotein of Issyk-Kul virus strain PbGER in comparison with selected members of the orthonairoviruses.
Figure 2
Figure 2
Allocation of available seuquences of Issyk-Kul virus PbGER on the respective segments.
Figure 3
Figure 3
Phylogenetic reconstruction of ISKV PbGER (L-segment 6650 nt) with other members of the Keterah group and of the family Nairoviridae.
See this image and copyright information in PMC

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