Multidisciplinary Approach to the Diagnosis and In-Hospital Management of COVID-19 Infection: A Narrative Review

doi:10.3389/fphar.2020.572168

Review

. 2020 Dec 9:11:572168.

doi: 10.3389/fphar.2020.572168. eCollection 2020.

Multidisciplinary Approach to the Diagnosis and In-Hospital Management of COVID-19 Infection: A Narrative Review

Affiliations

¹ Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
² Anesthesiology and Pain Department, Fondazione Istituto G.Giglio, Cefalù, Italy.
³ Emergency Medicine Fellowship Programme, University of Pavia, Pavia, Italy.
⁴ Emergency Department, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
⁵ Unità operativa Complessa di Pneumologia, A.O. Ospedali Riuniti Villa Sofia Cervello, Palermo, Italy.
⁶ San Marino State Hospital, Cailungo, San Marino Republic.
⁷ Cliniche Humanitas Gavazzeni, U.O. Elettrofisiologia, Bergamo, Italy.
⁸ Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.), Section of Anaesthesia, Analgesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, University of Palermo, Palermo, Italy.
⁹ Polyclinique du Maine, Laval, Pays de la Loire, France.
¹⁰ Section of Radiology, Department of Biomedicine, Neurosciences and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy.
¹¹ Struttura Complessa di Neurologia, Ospedale Santa Croce di Moncalieri, Asl TO5, Moncalieri (TO), Italy.

PMID: 33362541
PMCID: PMC7758731
DOI: 10.3389/fphar.2020.572168

Review

Multidisciplinary Approach to the Diagnosis and In-Hospital Management of COVID-19 Infection: A Narrative Review

Giuliano Lo Bianco et al. Front Pharmacol. 2020.

. 2020 Dec 9:11:572168.

doi: 10.3389/fphar.2020.572168. eCollection 2020.

Authors

Affiliations

¹ Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
² Anesthesiology and Pain Department, Fondazione Istituto G.Giglio, Cefalù, Italy.
³ Emergency Medicine Fellowship Programme, University of Pavia, Pavia, Italy.
⁴ Emergency Department, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
⁵ Unità operativa Complessa di Pneumologia, A.O. Ospedali Riuniti Villa Sofia Cervello, Palermo, Italy.
⁶ San Marino State Hospital, Cailungo, San Marino Republic.
⁷ Cliniche Humanitas Gavazzeni, U.O. Elettrofisiologia, Bergamo, Italy.
⁸ Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.), Section of Anaesthesia, Analgesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, University of Palermo, Palermo, Italy.
⁹ Polyclinique du Maine, Laval, Pays de la Loire, France.
¹⁰ Section of Radiology, Department of Biomedicine, Neurosciences and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy.
¹¹ Struttura Complessa di Neurologia, Ospedale Santa Croce di Moncalieri, Asl TO5, Moncalieri (TO), Italy.

PMID: 33362541
PMCID: PMC7758731
DOI: 10.3389/fphar.2020.572168

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or COVID-19 disease) was declared a pandemic on 11th March 2020 by the World Health Organization. This unprecedented circumstance has challenged hospitals' response capacity, requiring significant structural and organizational changes to cope with the surge in healthcare demand and to minimize in-hospital risk of transmission. As our knowledge advances, we now understand that COVID-19 is a multi-systemic disease rather than a mere respiratory tract infection, therefore requiring holistic care and expertise from various medical specialties. In fact, the clinical spectrum of presentation ranges from respiratory complaints to gastrointestinal, cardiac or neurological symptoms. In addition, COVID-19 pandemic has created a global burden of mental illness that affects the general population as well as healthcare practitioners. The aim of this manuscript is to provide a comprehensive and multidisciplinary insight into the complexity of this disease, reviewing current scientific evidence on COVID-19 management and treatment across several medical specialties involved in the in-hospital care of these patients.

Keywords: COVID-19; hospital care; hospital response capability; multispecialist care; pandemic (COVID-19).

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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References

1. Ambrose H.-T. F., Wong H. Y. F., Lam H. Y. S., Leung S. T., Chin T. W.-Y., Lo C. S. Y., et al. (2019). Frequency and distribution of chest radiographic findings in COVID-19 positive patients. Radiology 11, 201160 10.1148/radiol.2020201160 - DOI - PMC - PubMed
1. Antonelli M., Conti G., Moro M. L. (2001). Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multicenter study. Intens. Care Med. 27 (11), 1718–1728. 10.1007/s00134001-1114-4 - DOI - PubMed
1. Arabi Y. M. (2020). Critical care management of adults with community-acquired severe respiratory viral infection. Intens. Care Med. 46 (2), 315–323. 10.1007/s00134-020-05943-5 - DOI - PMC - PubMed
1. Asperges E., Novati S., Muzzi A., Biscarini S., Sciarra M., Lupi M., et al. (2020). The COVID19 IRCCS San Matteo Pavia Task Force, rapid response to COVID-19 outbreak in Northern Italy: how to convert a classic infectious disease ward into a COVID-19 response centre. J. Hosp. Infect. 14, 64–69. 10.1016/j.jhin.2020.03.020 - DOI - PMC - PubMed
1. Baig A. M., Khaleeq A., Ali U., Syeda H. (2020). Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms. ACS Chem. Neurosci. 7, 22–59. 10.1021/acschemneuro.0c00122 - DOI - PubMed

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[1] Ambrose H.-T. F., Wong H. Y. F., Lam H. Y. S., Leung S. T., Chin T. W.-Y., Lo C. S. Y., et al. (2019). Frequency and distribution of chest radiographic findings in COVID-19 positive patients. Radiology 11, 201160 10.1148/radiol.2020201160 - DOI - PMC - PubMed

[2] Ambrose H.-T. F., Wong H. Y. F., Lam H. Y. S., Leung S. T., Chin T. W.-Y., Lo C. S. Y., et al. (2019). Frequency and distribution of chest radiographic findings in COVID-19 positive patients. Radiology 11, 201160 10.1148/radiol.2020201160 - DOI - PMC - PubMed

[3] Antonelli M., Conti G., Moro M. L. (2001). Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multicenter study. Intens. Care Med. 27 (11), 1718–1728. 10.1007/s00134001-1114-4 - DOI - PubMed

[4] Antonelli M., Conti G., Moro M. L. (2001). Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multicenter study. Intens. Care Med. 27 (11), 1718–1728. 10.1007/s00134001-1114-4 - DOI - PubMed

[5] Arabi Y. M. (2020). Critical care management of adults with community-acquired severe respiratory viral infection. Intens. Care Med. 46 (2), 315–323. 10.1007/s00134-020-05943-5 - DOI - PMC - PubMed

[6] Arabi Y. M. (2020). Critical care management of adults with community-acquired severe respiratory viral infection. Intens. Care Med. 46 (2), 315–323. 10.1007/s00134-020-05943-5 - DOI - PMC - PubMed

[7] Asperges E., Novati S., Muzzi A., Biscarini S., Sciarra M., Lupi M., et al. (2020). The COVID19 IRCCS San Matteo Pavia Task Force, rapid response to COVID-19 outbreak in Northern Italy: how to convert a classic infectious disease ward into a COVID-19 response centre. J. Hosp. Infect. 14, 64–69. 10.1016/j.jhin.2020.03.020 - DOI - PMC - PubMed

[8] Asperges E., Novati S., Muzzi A., Biscarini S., Sciarra M., Lupi M., et al. (2020). The COVID19 IRCCS San Matteo Pavia Task Force, rapid response to COVID-19 outbreak in Northern Italy: how to convert a classic infectious disease ward into a COVID-19 response centre. J. Hosp. Infect. 14, 64–69. 10.1016/j.jhin.2020.03.020 - DOI - PMC - PubMed

[9] Baig A. M., Khaleeq A., Ali U., Syeda H. (2020). Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms. ACS Chem. Neurosci. 7, 22–59. 10.1021/acschemneuro.0c00122 - DOI - PubMed

[10] Baig A. M., Khaleeq A., Ali U., Syeda H. (2020). Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms. ACS Chem. Neurosci. 7, 22–59. 10.1021/acschemneuro.0c00122 - DOI - PubMed

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Multidisciplinary Approach to the Diagnosis and In-Hospital Management of COVID-19 Infection: A Narrative Review

Affiliations

Multidisciplinary Approach to the Diagnosis and In-Hospital Management of COVID-19 Infection: A Narrative Review

Authors

Affiliations

Abstract

Conflict of interest statement

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Cited by

References

Publication types

LinkOut - more resources

Full Text Sources

Research Materials

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