Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov 3;8(12):3658-3660.
doi: 10.1002/ccr3.3474. eCollection 2020 Dec.

Extranodal natural killer/T-cell lymphoma in an 11-year-old child

Affiliations

Extranodal natural killer/T-cell lymphoma in an 11-year-old child

Takeshi Ninchoji et al. Clin Case Rep. .

Abstract

Extranodal natural killer/T-cell lymphoma (ENKTL) is difficult to identify and diagnose appropriately. Positron emission tomography imaging is a crucial method that leads to precise diagnosis. A proper regimen including stem cell transplantation would possibly improve prognosis of advanced ENKTL.

Keywords: SMILE therapy; extranodal natural killer/T‐cell lymphoma; hemophagocytic syndrome.

PubMed Disclaimer

Conflict of interest statement

Kandai Nozu has received consulting fees from Kyowa Kirin Co., Ltd.; and lecture fees from Kyowa Kirin Co., Ltd., Novartis Pharmaceuticals Corporation, and Chugai Pharmaceutical Co., Ltd. Kazumoto Iijima has received grant support from Daiichi Sankyo Co., Ltd.; consulting fees from Kyowa Kirin Co., Ltd., and Boehringer Ingelheim; and lecture fees from Kyowa Kirin Co., Ltd., Chugai Pharmaceutical Co., Ltd., Takeda Pharmaceutical Company, Integrated Development Associates, and Novartis Pharmaceuticals Corporation. The other authors declare that no conflicts of interest exist.

Figures

FIGURE 1
FIGURE 1
PET‐MRI images. A, Whole scan showed abnormal accumulations in the sinusoid, lungs, and kidney. B‐D, Coronal images of each organ. B, sinusoid; C. lungs; D, kidney

References

    1. Henter JI, Horne A, Arico M, et al. HLH‐2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistocytosis. Pediatr Blood Cancer. 2007;48(2):124‐131. - PubMed
    1. Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127(20):2375‐2390. - PMC - PubMed
    1. Yamaguchi M, Kwong YL, Kim WS, et al. Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T‐cell lymphoma, nasal type: the NK‐Cell Tumor Study Group study. J Clin Oncol. 2011;29(33):4410‐4416. - PubMed
    1. Kim SJ, Park S, Kang ES, et al. Induction treatment with SMILE and consolidation with autologous stem cell transplantation for newly diagnosed stage IV extranodal natural killer/T‐cell lymphoma patients. Ann Hematol. 2015;94(1):71‐78. - PubMed

LinkOut - more resources