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Case Reports
. 2020 Dec 17;2020(12):rjaa481.
doi: 10.1093/jscr/rjaa481. eCollection 2020 Dec.

Two new cases of pediatric tumoral calcinosis

Lova Hasina Rajaonarison Ny Ony Narindra  1 , Vatosoa Sarobidy Nirinaharimanitra  2 , Francis Allen Hunald  2 , Ahmad Ahmad  1
Affiliations
Case Reports

Two new cases of pediatric tumoral calcinosis

Lova Hasina Rajaonarison Ny Ony Narindra et al. J Surg Case Rep. .

Abstract

Tumoral calcinosis (TC) is a rare benign pathology, particularly in pediatrics. It is difficult to diagnose with its pathophysiology poorly understood. We report two pediatric cases of TC having benefited from radiological assessments and surgical excision. Final diagnosis was made by pathological examination. For the two cases, no sign of recurrence was noted ~30 months of follow-up.

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Figures

Figure 1
Figure 1
X-ray of the pelvis in frontal view (a) and of the right elbow in profile (b); and CT-scan without contrast media of the pelvis in soft tissue window (c), showing a calcified, multi-lobed mass containing fluid components (asterisk) with liquid–liquid level (arrows) in the extra-articular soft tissues. Note: the absence of joint or bone lesion detected.
Figure 2
Figure 2
Microphotograph of the specimen hematoxylin and eosin (H–E stain, ×10) showing cystic lesion consisting of central granular or amorphous material, calcified, surrounded by a macrophage reaction with multinucleated giant cells and mononuclear inflammatory elements; associated with numerous osteoid deposits scattered in amorphous layers with surrounding non-inflammatory fibrous tissue.
Figure 3
Figure 3
Radiography in frontal view (a) and profile (b); and CT-scan in soft tissue window (c) and bone window (d) of the left ankle showing a calcified polylobed mass in the extra-articular soft tissues and the lower third of the leg.
Figure 4
Figure 4
Intraoperative photograph of the mass showing a whitish appearance (a) and microphotograph revealing calcified amorphous material, surrounded by a macrophage reaction with multinucleated giant cells and mononuclear inflammatory elements; associated with numerous osteoid deposits scattered in amorphous layers with surrounding non-inflammatory fibrous tissue (H–E stain, ~10).
See this image and copyright information in PMC

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