The complete chloroplast genome of the traditional Chinese herb, Uncaria rhynchophylla (Rubiaceae)
- PMID: 33366585
- PMCID: PMC7748432
- DOI: 10.1080/23802359.2019.1703597
The complete chloroplast genome of the traditional Chinese herb, Uncaria rhynchophylla (Rubiaceae)
Abstract
Uncaria rhynchophylla is a vine plant belonging to the family Rubiaceae and has been used as medicine for a long time in China. In this study, the complete chloroplast (cp) genome sequence of U. rhynchophylla was first reported and characterized. The cp genome was 154,605 bp in length and contains a pair of inverted repeats (IRs, 34,165 bp each) separated by a large (84,327 bp) and small (12,966 bp) single-copy regions. A total of 113 unique genes were predicted, including 79 protein-coding genes, 30 tRNA genes and 4 rRNA genes. The phylogenetic analysis suggested that U. rhynchophylla was closer to Neolamarckia cadamba.
Keywords: Chloroplast genome; Rubiaceae; Uncaria rhynchophylla; phylogenetic analysis.
© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
Conflict of interest statement
No potential conflict of interest was reported by the authors.
Figures

Similar articles
-
The complete chloroplast genome of Uncaria macrophylla Wall. (Rubiaceae) and its phylogenetic analysis.Mitochondrial DNA B Resour. 2022 May 13;7(5):867-869. doi: 10.1080/23802359.2022.2075711. eCollection 2022. Mitochondrial DNA B Resour. 2022. PMID: 35602328 Free PMC article.
-
The complete chloroplast genome sequence of traditional Chinese medicine Uncaria macrophylla (Rubiaceae).Mitochondrial DNA B Resour. 2022 Apr 24;7(4):694-695. doi: 10.1080/23802359.2022.2048215. eCollection 2022. Mitochondrial DNA B Resour. 2022. PMID: 35493711 Free PMC article.
-
The complete chloroplast genome of the multipurpose and traditional herb, Ruta graveolens L.Mitochondrial DNA B Resour. 2019 Oct 18;4(2):3661-3662. doi: 10.1080/23802359.2019.1678426. Mitochondrial DNA B Resour. 2019. PMID: 33366131 Free PMC article.
-
Characterization and Comparative Analysis of Chloroplast Genomes in Five Uncaria Species Endemic to China.Int J Mol Sci. 2022 Oct 1;23(19):11617. doi: 10.3390/ijms231911617. Int J Mol Sci. 2022. PMID: 36232915 Free PMC article.
-
The beneficial pharmacological effects of Uncaria rhynchophylla in neurodegenerative diseases: focus on alkaloids.Front Pharmacol. 2024 Jul 31;15:1436481. doi: 10.3389/fphar.2024.1436481. eCollection 2024. Front Pharmacol. 2024. PMID: 39170707 Free PMC article. Review.
Cited by
-
Chloroplast genome characterization of Uncaria guianensis and Uncaria tomentosa and evolutive dynamics of the Cinchonoideae subfamily.Sci Rep. 2023 May 24;13(1):8390. doi: 10.1038/s41598-023-34334-1. Sci Rep. 2023. PMID: 37225737 Free PMC article.
-
Evaluation of Reference Genes for Normalizing RT-qPCR and Analysis of the Expression Patterns of WRKY1 Transcription Factor and Rhynchophylline Biosynthesis-Related Genes in Uncaria rhynchophylla.Int J Mol Sci. 2023 Nov 15;24(22):16330. doi: 10.3390/ijms242216330. Int J Mol Sci. 2023. PMID: 38003520 Free PMC article.
-
The complete chloroplast genome of Gardenia stenophylla Merr (Rubiaceae) and its phylogenetic analysis.Mitochondrial DNA B Resour. 2024 Aug 12;9(8):1039-1043. doi: 10.1080/23802359.2024.2389918. eCollection 2024. Mitochondrial DNA B Resour. 2024. PMID: 39139657 Free PMC article.
-
Therapeutic Potential of Natural Products in Treating Neurodegenerative Disorders and Their Future Prospects and Challenges.Molecules. 2021 Sep 2;26(17):5327. doi: 10.3390/molecules26175327. Molecules. 2021. PMID: 34500759 Free PMC article. Review.
-
Mitogenome of Uncaria rhynchophylla: genome structure, characterization, and phylogenetic relationships.BMC Genomics. 2025 Feb 26;26(1):199. doi: 10.1186/s12864-025-11372-9. BMC Genomics. 2025. PMID: 40012082 Free PMC article.
References
-
- Bremer B. 2009. A review of molecular phylogenetic studies of Rubiaceae. Ann Mo Bot Gard. 96(1):4–26.
-
- Fujiwara H, Iwasaki K, Furukawa K, Seki T, He M, Maruyama M, Tomita N, Kudo Y, Higuchi M, Saido TC, et al. . 2006. Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's β-amyloid proteins. J Neurosci Res. 84(2):427–433. - PubMed
-
- Geng CA, Yang TH, Huang XY, Ma YB, Zhang XM, Chen JJ.. 2019. Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors. J Ethnopharmacol. 232(25):39–46. - PubMed
LinkOut - more resources
Full Text Sources
Miscellaneous