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. 2020 Oct 20;64(4):523-529.
doi: 10.2478/jvetres-2020-0067. eCollection 2020 Dec.

Efficacy of Natural Formulations in Bovine Mastitis Pathology: Alternative Solution to Antibiotic Treatment

Claudia Pașca  1 , Liviu Alexandru Mărghitaș  1 , Daniel Severus Dezmirean  1 , Ioana Adriana Matei  2 , Victorița Bonta  3 , Ioan Pașca  4 , Flore Chirilă  2 , Adrian Cîmpean  4 , Nicodim Iosif Fiț  2
Affiliations

Efficacy of Natural Formulations in Bovine Mastitis Pathology: Alternative Solution to Antibiotic Treatment

Claudia Pașca et al. J Vet Res. .

Abstract

Introduction: Bovine mastitis is an inflammatory disease of the udder that causes important economic losses in the animal breeding and dairy product industries. Nowadays, the conventional livestock antibiotic treatments are slowly being replaced by alternative treatments. In this context, the main aim of this study was to evaluate the efficacy of natural products in alternative treatment of bovine mastitis.

Material and methods: Two natural formulations with previously suggested in vitro antimicrobial effect were tested in vivo on mastitic cows. Animals with a positive diagnosis for mastitis (n = 20) were divided into three treatment groups: two groups (n = 8) were administered formulations of propolis, alcoholic extracts of Brewers Gold and Perle hops, plum lichen, common mallow, marigold, absinthe wormwood, black poplar buds, lemon balm, and essential oils of oregano, lavender, and rosemary designated R4 and R7 (differing only in the latter being more concentrated) and one group (n = 4) a conventional antibiotic mixture. In vivo efficacy of treatments was evaluated by somatic cell and standard plate counts, the treatment being considered efficacious when both parameters were under the maximum limit.

Results: R7 was effective in the most cases, being therapeutically bactericidal in six out of eight cows, while R4 gave good results in three out of eight cows, and conventional antibiotics cured one out of four.

Conclusion: These results suggest the possible therapeutic potential of these natural products in bovine mastitis.

Keywords: alternative treatment; cows; in vivo testing; mastitis; natural products.

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Conflict of interest statement

Conflict of Interest Conflict of Interests Statement: The authors declare that there is no conflict of interests regarding the publication of this article.

Figures

Fig.1
Fig.1
Number of colony-forming units (CFU) in milk from mastitic cows treated with two different natural plant-based formulations and conventional antibiotics
Fig. 2
Fig. 2
Somatic cells count (SCC) in quarter milk samples from cows treated with two different natural plant-based formulations and conventional antibiotics
See this image and copyright information in PMC

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