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Review
. 2021 Mar;38(2):351-358.
doi: 10.1111/pde.14503. Epub 2020 Dec 27.

Light-based treatment of pediatric port-wine birthmarks

Jennifer M Tran  1 , Kristen M Kelly  2 , Beth A Drolet  1 , Andrew C Krakowski  3 , Lisa M Arkin  1
Affiliations
Free article
Review

Light-based treatment of pediatric port-wine birthmarks

Jennifer M Tran et al. Pediatr Dermatol. 2021 Mar.
Free article

Abstract

Port-wine birthmarks (PWBs) are progressive vascular malformations with significant disfigurement and psychosocial morbidity; early light-based treatment has shown improved outcomes in the pediatric population. Somatic mosaic mutations underly the progressive nature of PWBs and explain the significant differences in response and heterogeneity of vessel architecture in the pediatric population when compared to the adult cohort. Here, we summarize a review of pediatric specific literature on the various light-based treatment modalities, including pulsed dye laser, near-infrared lasers, and intense pulsed light, providing the various indications, tips, advantages, and disadvantages for the pediatric dermatologist.

Keywords: developmental defects; genetic diseases/mechanisms; laser; vascular malformation.

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References

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