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Review
. 2021 Jul;74(1):483-490.
doi: 10.1002/hep.31697. Epub 2021 Jun 28.

Perspectives on the Neoadjuvant Use of Immunotherapy in Hepatocellular Carcinoma

Affiliations
Review

Perspectives on the Neoadjuvant Use of Immunotherapy in Hepatocellular Carcinoma

David J Pinato et al. Hepatology. 2021 Jul.
No abstract available

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References

    1. Finn RS, Qin S, Ikeda M, Galle PR, Ducreux M, Kim TY, et al. Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma. N Engl J Med 2020;382:1894-1905. https://pubmed.ncbi.nlm.nih.gov/32402160/. Accessed June 26, 2020.
    1. Zhu AX, Finn RS, Ikeda M, Sung MW, Baron AD, Kudo M, et al. A phase Ib study of lenvatinib (LEN) plus pembrolizumab (PEMBRO) in unresectable hepatocellular carcinoma (uHCC). J Clin Oncol 2020;38(Suppl. 15):4519.
    1. Bruix J, Takayama T, Mazzaferro V, Chau GY, Yang J, Kudo M, et al. Adjuvant sorafenib for hepatocellular carcinoma after resection or ablation (STORM): a phase 3, randomised, double-blind, placebo-controlled trial. Lancet Oncol 2015;16:1344-1354. https://pubmed.ncbi.nlm.nih.gov/26361969/. Accessed September 28, 2020.
    1. Salmon H, Idoyaga J, Rahman A, Leboeuf M, Remark R, Jordan S, et al. Expansion and activation of CD103+ dendritic cell progenitors at the tumor site enhances tumor responses to therapeutic PD-L1 and BRAF inhibition. Immunity 2016;44:924-938. https://pubmed.ncbi.nlm.nih.gov/27096321/. Accessed September 28, 2020.
    1. Sánchez-Paulete AR, Cueto FJ, Martínez-López M, Labiano S, Morales-Kastresana A, Rodríguez-Ruiz ME, et al. Cancer immunotherapy with immunomodulatory anti-CD137 and anti-PD-1 monoclonal antibodies requires BATF3-dependent dendritic cells. Cancer Discov 2016;6:71-79. https://pubmed.ncbi.nlm.nih.gov/26493961/. Accessed September 28, 2020.

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