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. 2021 Jan 1;147(1):219-230.
doi: 10.1097/PRS.0000000000007509.

Platelet-Rich Plasma: Evolving Role in Plastic Surgery

Edward S Chamata  1 , Erica L Bartlett  1 , David Weir  1 , Rod J Rohrich  1
Affiliations

Platelet-Rich Plasma: Evolving Role in Plastic Surgery

Edward S Chamata et al. Plast Reconstr Surg. .

Abstract

Background: The use of platelet-rich plasma has emerged as one of the most desired nonsurgical treatments for facial rejuvenation and hair restoration. It has grown to encompass a wide variety of applications within the field of plastic surgery, including its use in combination with microneedling, laser, and fat-grafting procedures.

Methods: In this article, the authors aim to (1) describe the preparation process of platelet-rich plasma; (2) discuss the proposed science behind platelet-rich plasma with regard to its evolving role in hair restoration and facial rejuvenation; and (3) highlight the recent literature examining its widespread use.

Results: Based on the available literature, there is a therapeutic advantage to the use of platelet-rich plasma as a single treatment modality for alopecia and skin rejuvenation and in combination with laser skin treatment and fat grafting. There is, however, a considerable amount of variability in the processing, preparation, and treatment modalities.

Conclusions: Despite a lack of standardized protocols for platelet-rich plasma preparation and a scarcity of large-scale studies with long-term follow-up, there is convincing evidence with objective measurement modalities that display positive outcomes after treatment for skin rejuvenation, hair regrowth, wound healing, and fat graft take.

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Comment in

  • Platelet-Rich Plasma: Evolving Role in Plastic Surgery.
    Annacontini L, Verdura V, Di Pace B, Parisi D, Portincasa A. Annacontini L, et al. Plast Reconstr Surg. 2022 Feb 1;149(2):347e-349e. doi: 10.1097/PRS.0000000000008760. Plast Reconstr Surg. 2022. PMID: 34965221 No abstract available.

References

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    1. Motosko CC, Khouri KS, Poudrier G, Sinno S, Hazen A. Evaluating platelet-rich therapy for facial aesthetics and alopecia: A critical review of the literature. Plast Reconstr Surg. 2018;141:1115–1123.
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