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Case Reports
. 2020 Dec 22;13(12):e236041.
doi: 10.1136/bcr-2020-236041.

Infliximab-induced optic neuritis

Andrew Dermawan  1 , Kenji So  2 , Kannan Venugopal  2 , Sherman Picardo  2
Affiliations
Case Reports

Infliximab-induced optic neuritis

Andrew Dermawan et al. BMJ Case Rep. .

Abstract

Antitumour necrosis factor alpha agents are important treatments in many inflammatory conditions including rheumatoid arthritis, psoriatic arthritis and the inflammatory bowel diseases. However, there have been case reports of optic neuritis and other demyelinating diseases as complications of these agents. This case report presents a patient with ulcerative colitis on infliximab who presented with sudden onset mono-ocular visual field loss and highlights the diagnosis and management of infliximab-induced optic neuritis.

Keywords: biological agents; drugs: CNS (not psychiatric); inflammatory bowel disease; neuroopthalmology; visual pathway.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
MRI head and optic nerve. T2 axial image of MRI head (black arrow): bulging of the left optic nerve head. White arrow: fluid around the optic nerve sheath bilaterally, left more than right.
Figure 2
Figure 2
MRI head. An axial view of his MRI head.
Figure 3
Figure 3
MRI head. Another axial view of his MRI head.
Figure 4
Figure 4
Right eye visual field.
Figure 5
Figure 5
Left eye visual field.
Figure 6
Figure 6
Right eye funduscopy.
Figure 7
Figure 7
Left eye funduscopy.
Figure 8
Figure 8
Right eye optical coherence tomography.
Figure 9
Figure 9
Left eye optical coherence tomography. RNFL, Retinal Nerve Fiber Layer.
See this image and copyright information in PMC

References

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