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. 2020 Dec 18;99(51):e23682.
doi: 10.1097/MD.0000000000023682.

The effect of enhancing quality of life in patients intervention for advanced lung cancer: Protocol for a randomized clinical study

Xianhong Li  1 , Ke Qin  1 , Chunyan Yuan  2 , Shiqiang Song  1
Affiliations

The effect of enhancing quality of life in patients intervention for advanced lung cancer: Protocol for a randomized clinical study

Xianhong Li et al. Medicine (Baltimore). .

Expression of concern in

  • Expression of Concern: Study Protocols.
    [No authors listed] [No authors listed] Medicine (Baltimore). 2025 Nov 7;104(45):e46330. doi: 10.1097/MD.0000000000046330. Medicine (Baltimore). 2025. PMID: 41204616 Free PMC article. No abstract available.

Abstract

Objective: The objective of this present research is to evaluate the effect of the intervention of enhancing quality of life in patients in patients with advanced lung cancer.

Methods: Our research is carried out as a randomized clinical trial which will be implemented from December 2020 to October 2021. It was approved by the Ethics Committee of People's Hospital of Chengyang District (03982790). This study includes 90 patients with advanced lung cancer. Patients diagnosed at our oncology clinic are eligible if they are diagnosed within 8 weeks of a novel diagnosis of stage 3 or stage 4 lung cancer. Patients with hepatic insufficiency, renal failure, and respiratory and heart failure, as well as a series of severe mental illness are excluded from our research. Patients are divided randomly into the intervention group and control group, each group is assigned 45 patients. Through utilizing functional assessment of cancer therapy-lung, the measurement of life quality is conducted. And the measurement of mood is carried out with Hospital Anxiety and Depression Scale.

Results: Table 1 indicates the patient's life quality and Hospital Anxiety and Depression Scale in both groups.

Conclusion: Enhancing quality of life in patient intervention may be beneficial to improve the life quality in advanced lung cancer patients.Trial registration: The protocol was registered in Research Registry (researchregistry6243).

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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