Prior SARS-CoV-2 infection is associated with protection against symptomatic reinfection
- PMID: 33373652
- PMCID: PMC7832116
- DOI: 10.1016/j.jinf.2020.12.023
Prior SARS-CoV-2 infection is associated with protection against symptomatic reinfection
Abstract
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Whether SARS-CoV-2 infection confers immunity to reinfection is uncertain.
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The ‘second wave’ of transmission offered an opportunity to examine this.
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We observed no symptomatic reinfections in a cohort of healthcare workers.
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This apparent immunity to re-infection was maintained for at least 6 months.
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Further studies are required to define immunological mechanism(s) and durability.
Keywords: Antibody; COVID-19; Healthcare workers; Immunity; Protection.
Comment in
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Prior COVID-19 significantly reduces the risk of subsequent infection, but reinfections are seen after eight months.J Infect. 2021 Apr;82(4):e11-e12. doi: 10.1016/j.jinf.2021.01.005. Epub 2021 Jan 13. J Infect. 2021. PMID: 33450303 Free PMC article.
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Is COVID-19 severity associated with anti-spike antibody duration? Data from the ARCOVID prospective observational study.J Infect. 2021 May;82(5):e28-e30. doi: 10.1016/j.jinf.2021.01.023. Epub 2021 Feb 3. J Infect. 2021. PMID: 33545166 Free PMC article. No abstract available.
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Details of SARS-CoV-2 reinfections at a major UK tertiary centre.J Infect. 2021 Jun;82(6):e29-e30. doi: 10.1016/j.jinf.2021.03.004. Epub 2021 Mar 17. J Infect. 2021. PMID: 33744302 Free PMC article. No abstract available.
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Incidence of delayed asymptomatic COVID-19 recurrences in a 6-month longitudinal study.J Infect. 2021 Jun;82(6):276-316. doi: 10.1016/j.jinf.2021.03.020. Epub 2021 Mar 29. J Infect. 2021. PMID: 33794262 Free PMC article. No abstract available.
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Persistence of humoral immune response to SARS-CoV-2 up to 7 months post-infection: Cross-sectional study, South India, 2020-21.J Infect. 2021 Sep;83(3):381-412. doi: 10.1016/j.jinf.2021.05.026. Epub 2021 May 28. J Infect. 2021. PMID: 34058261 Free PMC article. No abstract available.
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Serological profile of first SARS-CoV-2 reinfection cases detected within the SIREN study.J Infect. 2022 Feb;84(2):248-288. doi: 10.1016/j.jinf.2021.09.019. Epub 2021 Sep 30. J Infect. 2022. PMID: 34600935 Free PMC article. No abstract available.
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