Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Dec 1;38(6):681-686.
doi: 10.7518/hxkq.2020.06.013.

[Gene polymorphism in oral lichen planus]

[Article in Chinese]
Ying-Xiao Pan  1 , Da-Wei Guo  1 , Xin Li  1 , Heng-Yi Liu  1 , Shu-Lai Lu  1
Affiliations

[Gene polymorphism in oral lichen planus]

[Article in Chinese]
Ying-Xiao Pan et al. Hua Xi Kou Qiang Yi Xue Za Zhi. .

Abstract
in English, Chinese

Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa. The prevalence rate of OLP in adults is 0.5%-2%. The etiology and pathogenesis of OLP are still unclear. The pathogenesis of OLP may be related to the genetic polymorphism of some genes. Currently, the gene families, including tumor necrosis factor, interferon, interleukin, enzyme, and receptor, have been extensively studied. This work reviews related studies on gene polymorphism of OLP.

口腔扁平苔藓（OLP）是一种常见的口腔黏膜慢性炎症性疾病，成年人患病率为0.5%~2%。OLP的病因和发病机制尚不明确，研究显示其发病可能与某些基因的遗传多态性相关，目前研究较多的有肿瘤坏死因子、干扰素、白细胞介素、酶类、受体等基因家族。本文就基因多态性与口腔扁平苔藓的相关性进行综述。.

Keywords: etiology; gene polymorphism; genetics; oral lichen planus.

PubMed Disclaimer

Conflict of interest statement

利益冲突声明：作者声明本文无利益冲突。

References

    1. Alrashdan MS, Cirillo N, McCullough M. Oral lichen planus: a literature review and update[J] Arch Dermatol Res. 2016;308(8):539–551. - PubMed
    1. 陈 谦明. 口腔黏膜病学[M] 4版. 北京: 人民卫生出版社; 2012.
    2. Chen QM. Oral medicine[M] 4th ed. Beijing: People's Medical Publishing House; 2012.
    1. Al-Hashimi I, Schifter M, Lockhart PB, et al. Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations[J] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(Suppl):S25.e1–S25.e12. - PubMed
    1. Ismail SB, Kumar SK, Zain RB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation[J] J Oral Sci. 2007;49(2):89–106. - PubMed
    1. Sugermann PB, Savage NW, Seymour GJ, et al. Is there a role for tumor necrosis factor-alpha (TNF-alpha) in oral lichen planus[J] J Oral Pathol Med. 1996;25(5):219–224. - PubMed

Substances

LinkOut - more resources