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Review
. 2021 Jun;142(3):283-292.
doi: 10.1007/s10633-020-09799-4. Epub 2020 Dec 31.

The contribution of multifocal visual evoked potentials in patients with optic neuritis and multiple sclerosis: a review

Paraskevas Zafeiropoulos  1 , Andreas Katsanos  2 , George Kitsos  2 , Maria Stefaniotou  2 , Ioannis Asproudis  2
Affiliations
Review

The contribution of multifocal visual evoked potentials in patients with optic neuritis and multiple sclerosis: a review

Paraskevas Zafeiropoulos et al. Doc Ophthalmol. 2021 Jun.

Abstract

Purpose: To review the evidence on the usefulness of the multifocal visual evoked potential (mfVEP) test in patients with optic neuritis (ON) and/or multiple sclerosis (MS).

Methods: We critically review key published evidence on the use of mfVEP in ON/MS patients and its association with other functional and structural tests.

Results: Multifocal VEP tests are useful in detecting abnormality in patients with ON/MS and monitor the progression of lesions (remyelination, atrophy). In addition, mfVEP has good correlation with conventional visual evoked potential (VEP), standard automated perimetry, optical coherence tomography and magnetic resonance imaging. In patients with ON, mfVEP might be useful in predicting the risk of conversion to MS.

Keywords: Multifocal visual evoked potential (mfVEP); Multiple sclerosis (MS); Optic neuritis (ON).

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Conflict of interest statement

Authors Paraskevas Zafeiropoulos, George Kitsos, Maria Stefaniotou and Ioannis Asproudis declare that they have no conflict of interest. Andreas Katsanos declares honoraria and congress expenses by Santen, Vianex, Laboratoires Théa, Cooper and research support from Laboratoires Théa.

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