The effect of gastric distension on the secretion of acid and pepsin by patients with duodenal ulcer
- PMID: 333847
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The effect of gastric distension on the secretion of acid and pepsin by patients with duodenal ulcer
Acta Hepatogastroenterol (Stuttg).
1977 Aug.
Abstract
Twentyfour patients with active duodenal ulceration were subjected to gastric distension with a balloon, in an attempt to assess the "neural tone" affecting the parietal and chief cells of the stomach. Distension stimulated gastric secretion in a manner similar to, but weaker than, pentagastrin. No evidence was found that distension provides a specific "neural" stimulus to the gastric secretion of acid or pepsin in man.
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