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. 1977 Aug;24(4):271-7.

The effect of gastric distension on the secretion of acid and pepsin by patients with duodenal ulcer

J H Saunders, K G Wromsley
  • PMID: 333847

The effect of gastric distension on the secretion of acid and pepsin by patients with duodenal ulcer

J H Saunders et al. Acta Hepatogastroenterol (Stuttg). 1977 Aug.

Abstract

Twentyfour patients with active duodenal ulceration were subjected to gastric distension with a balloon, in an attempt to assess the "neural tone" affecting the parietal and chief cells of the stomach. Distension stimulated gastric secretion in a manner similar to, but weaker than, pentagastrin. No evidence was found that distension provides a specific "neural" stimulus to the gastric secretion of acid or pepsin in man.

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