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. 2021 Jan;16(1):558-560.
doi: 10.1016/j.jds.2020.06.006. Epub 2020 Jun 10.

Langerhans cell histiocytosis in an old man - Case report

Ming-Jay Hwang  1   2 , Bing-Wei Huang  1 , Yi-Pang Lee  1 , Chun-Pin Chiang  1   2   3
Affiliations

Langerhans cell histiocytosis in an old man - Case report

Ming-Jay Hwang et al. J Dent Sci. 2021 Jan.
No abstract available

Keywords: Langerhans cell histiocytosis; Mandible; Maxilla; Skull bone.

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Conflict of interest statement

The authors have no conflicts of interest relevant to this article.

Figures

Figure 1
Figure 1
Radiographic, clinical and histological photographs of our case of Langerhans cell histiocytosis. (A and B) Radiographic photographs showing multiple punched-out radiolucent lesions in the mandible and skull bone as well as a scooped-out appearance at the alveolar ridge of the mandible. (C) Clinical photograph demonstrating multiple granulation tissue-like masses on the edentulous mandibular alveolar ridge mucosa. (D and E) Microphotographs exhibiting a sheet of pale-staining histiocyte-like cells intermixed with numerous lymphocytes, plasma cells, and eosinophils as well as occasional multinucleated giant cells. The histiocyte-like cells possessed coffee bean-like or indented vesicular nuclei and pink cytoplasm (Hematoxylin and Eosin stain; original magnification, C, 10× and D, 20×). (F and G) Immunostained microphotographs revealing that the histiocyte-like cells were positive for CD1a (F, original magnification, 20×) and S-100 protein (G, original magnification, 20×). (H) Clinical photograph demonstrating a healed edentulous mandibular alveolar ridge mucosa with complete regression of the granulation tissue-like masses.
See this image and copyright information in PMC

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