Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb;36(1):209-213.
doi: 10.1007/s10877-020-00638-0. Epub 2021 Jan 1.

Accuracy of a battery-powered portable capnometer in premature infants

Affiliations

Accuracy of a battery-powered portable capnometer in premature infants

Eiji Hirakawa et al. J Clin Monit Comput. 2022 Feb.

Abstract

Carbon dioxide measurement is useful for confirmation of successful tracheal intubation and ensuring adequate ventilation. There are two types of CO2 detectors, i.e., single-use-only colorimetric devices and capnometers. Although portable capnometers are widely used for resuscitation, there have been no reports regarding their clinical utility in neonates. The correspondence between end-tidal CO2 (PetCO2) level determined using a battery-powered portable capnometer and arterial CO2 (PaCO2) was investigated using paired data obtained simultaneously from 26 neonates weighing 1262 ± 589 g at examination on mechanical ventilation. PetCO2 level and PaCO2 showed a strong correlation (r = 0.839, P < 0.001), and the correlation equation was: PetCO2 = 0.8 × PaCO2 + 1.1. Therefore, PetCO2 readings obtained with a battery-powered portable capnometer were likely to be underestimated. This became more pronounced with decreasing infant body weight at examination as the net difference in measurements of PaCO2 and PetCO2 was significantly positively correlated with infant body weight at examination (r = 0.451, P < 0.001). The observations presented here may be helpful in the use of battery-powered portable capnometers in neonates requiring controlled ventilation with tracheal intubation.

Keywords: Capnometer; End-tidal CO2; Premature infants.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Correlations between PaCO2 and PetCO2
Fig. 2
Fig. 2
Correlation between infant body weight and net difference in PaCO2–PetCo2

References

    1. Gavin A, Finn D, Mmoloki K, Livingstone V, O’Toole JM, Boylan GB, et al. J Pediatr. 2017;182:74–78. doi: 10.1016/j.jpeds.2016.11.006. - DOI - PubMed
    1. Chandrasekharan PK, Rawat M, Nair J, Gugino SF, Koenigsknecht C, Swartz DD, et al. Continuous end-tidal carbon dioxide monitoring during resuscitation of asphyxiated term lambs. Neonatology. 2016;109(4):265–273. doi: 10.1159/000443303. - DOI - PMC - PubMed
    1. Georgiou AP, Gouldson S, Amphlett AM. The use of capnography and the availability of airway equipment on Intensive Care Units in the UK and the Republic of Ireland. Anaesthesia. 2010;65:462–467. doi: 10.1111/j.1365-2044.2010.06308.x. - DOI - PubMed
    1. Levine RL, Wayne MA, Miller CC. End-tidal carbon dioxide and outcome of out-of-hospital cardiac arrest. N Engl J Med. 1997;337:301–306. doi: 10.1056/NEJM199707313370503. - DOI - PubMed
    1. Singh S, William D, Shekhar T, Mananda S. Utility of a novel quantitative handheld microstream capnometer during transport of critically ill children. Am J Emerg Med. 2006;24:302–307. doi: 10.1016/j.ajem.2005.10.024. - DOI - PubMed

LinkOut - more resources