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. 2021 Mar:104:510-525.
doi: 10.1016/j.ijid.2020.12.068. Epub 2020 Dec 29.

Prevalence of HIV, HCV and HBV in Central Asia and the Caucasus: A systematic review

Salima Davlidova  1 , Zoë Haley-Johnson  2 , Kate Nyhan  3 , Ayesha Farooq  4 , Sten H Vermund  5 , Syed Ali  6
Affiliations

Prevalence of HIV, HCV and HBV in Central Asia and the Caucasus: A systematic review

Salima Davlidova et al. Int J Infect Dis. 2021 Mar.

Abstract

Background: Human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) are substantial public health threats in the region of Central Asia and the Caucasus, where the prevalence of these infections is currently rising.

Methods: A systematic review of MEDLINE, Embase and PsycINFO was conducted with no publication date or language restrictions through October 2019. Additional data were also harvested from national surveillance reports, references found in discovered sources, and other "grey" literature. It included studies conducted on high-risk populations (people who inject drugs (PWID), female sex workers (FSW), men who have sex with men (MSM), prisoners, and migrants) in Central Asia: Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan; and the Caucasus: Armenia, Azerbaijan, Georgia, and Northern Caucasus region of the Russian Federation.

Results: Wide ranges were noted for HIV prevalence: PWID 0-30.1%, MSM 0-25.1%, prisoners 0-22.8%, FSW 0-10.0%, and migrants 0.06-1.5%, with the highest prevalence of these high-risk groups reported in Kazakhstan (for PWID), Georgia (for MSM and prisoners) and Uzbekistan (for migrants). HCV prevalence also had a wide range: PWID 0.3-92.1%, MSM 0-18.9%, prisoners 23.8-49.7%, FSW 3.3-17.8%, and migrants 0.5-26.5%, with the highest prevalence reported in Georgia (92.1%), Kyrgyzstan (49.7%), and migrants from Tajikistan and Uzbekistan (26.5%). Similarly, HBV prevalence had a wide range: PWID 2.8-79.7%, MSM 0-22.2%, prisoners 2.7-6.2%, FSW 18.4% (one study), and migrants 0.3-15.7%.

Conclusion: In Central Asia and the Caucasus, prevalence of HIV, HCV and HBV remains exceedingly high among selected populations, notably PWID and MSM.

Keywords: Caucasus; Central Asia; Hepatitis B virus; Hepatitis C virus; Human immunodeficiency virus.

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Conflict of interest statement

Conflict of Interest

None.

Figures

Figure 1.
Figure 1.
Map of the Central Asia and Caucasus. Area of research interest is marked in green. North Caucasus (also in green) is a part of the Russian Federation (in yellow).
Figure 2.
Figure 2.
PRISMA chart.
See this image and copyright information in PMC

References

    1. Abdourakhmanov DT, Hasaev AS, Castro FJ, Guardia J. Epidemiological and clinical aspects of hepatitis C virus infection in the Russian Republic of Daghestan. Eur J Epidemiol 1998;14(6):549–53. - PubMed
    1. Agadjanian V, Markosyan K. Male labor migration, patriarchy, and the awareness-behavior gap: HIV risks and prevention among migrants’ wives in Armenia. AIDS Care 2017;29(6):705–10. - PubMed
    1. Alexandrov D, Kostenko V, Ponarin E. Caucasus and Central Asia. Course for Social Workers. Part 2. Designed for Assistance in Practical Work with Migrants from Central Asia and the Caucasus]. Available from:. 1st ed. Moscow: International Labour Organization; 2012. https://www.ilo.org/wcmsp5/groups/public/-europe/-ro-geneva/-sro-moscow/....
    1. Alibayeva G, Todd CS, Khakimov MM, Giyasova GM, Botros BA, Carr JK, et al. Sexually transmitted disease symptom management behaviours among female sex workers in Tashkent, Uzbekistan. Int J STD AIDS 2007;18(5):324–8. - PubMed
    1. AlSalih ND, Sychev DA, Potemkin IA, Kyuregyan KK, Mikhailov MI. The prevalence of serological markers of viral hepatitis among labor migrants arriving in the Russian Federation. J Infectol 2017;9(2).

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