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. 2021 Mar:199:10-13.
doi: 10.1016/j.thromres.2020.12.015. Epub 2020 Dec 29.

The effect of race on composite thrombotic events in patients with COVID-19

Charles Esenwa  1 , Santiago R Unda  2 , David J Altschul  3 , Nikunj K Patel  4 , Avinash Malaviya  4 , Johanna Seiden  5 , Andrea Lendaris  5 , Khadean Moncrieffe  5 , Daniel L Labovitz  5
Affiliations

The effect of race on composite thrombotic events in patients with COVID-19

Charles Esenwa et al. Thromb Res. 2021 Mar.

Abstract

COVID-19 associated coagulopathy and mortality related to thrombotic complications have been suggested as biological mediators in racial disparities related to COVID-19. We studied the adjusted prevalence of acute ischemic stroke, pulmonary embolism, myocardial infarction, and deep venous thrombosis stratified by race in hospitalized patients in one New York City borough during the local COVID-19 surge. The multi-racial cohort included 4299 patients hospitalized with COVID-19, 9% of whom were white, 40% black, 41% Hispanic and 10% Asian or other. We found a 6.1% prevalence of composite thrombotic events. There were no significant race-specific differences in thrombotic events when adjusting for basic demographics, socioeconomic factors, medical comorbidities or biomarkers using a stepwise regression model. We therefore found no evidence that the racial disparities related to COVID-19, and specifically thrombotic complications, are caused by biological differences in race.

Keywords: COVID-19; Racial disparities; Stroke; Thrombosis.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Thrombotic event prevalence stratified by race. P values: ischemic stroke 0.792, pulmonary embolism 0.784, deep vein thrombosis 0.724, myocardial infarction 0.264, composite events 0.967.
See this image and copyright information in PMC

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