Principles of Care for Young Adults With Co-Occurring Psychiatric and Substance Use Disorders
- PMID: 33386320
- PMCID: PMC8276159
- DOI: 10.1542/peds.2020-023523F
Principles of Care for Young Adults With Co-Occurring Psychiatric and Substance Use Disorders
Abstract
Over 50% of young adults (defined as individuals aged 18-25 years) with substance use disorders (SUDs) have at least 1 co-occurring psychiatric disorder, and the presence of co-occurring disorders worsens SUD outcomes. Treatment of both co-occurring psychiatric disorders and SUDs in young adults is imperative for optimal treatment, yet many barriers exist to achieving this goal. We present a series of evidence-informed principles of care for young adults with co-occurring psychiatric disorders derived by a workgroup of experts convened by Boston Medical Center's Grayken Center for Addiction. The 3 principles are as follows: (1) young adults should receive integrated mental health and addiction care across treatment settings; (2) care should be responsive to the needs of young adults exposed to trauma and other adverse childhood experiences; and (3) treatment programs should regularly assess and respond to the evolving mental health needs, motivations, and treatment goals of young adults with co-occurring disorders. Our guidance for each principle is followed by a review of the evidence supporting that principle, as well as practice considerations for implementation. More research among young adults is critical to identify effective treatments and service systems for those with co-occurring disorders.
Copyright © 2021 by the American Academy of Pediatrics.
Conflict of interest statement
POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose.
Figures


Similar articles
-
Principles of Care for Young Adults With Substance Use Disorders.Pediatrics. 2021 Jan;147(Suppl 2):S195-S203. doi: 10.1542/peds.2020-023523B. Pediatrics. 2021. PMID: 33386322 Free PMC article.
-
The Justice System and Young Adults With Substance Use Disorders.Pediatrics. 2021 Jan;147(Suppl 2):S249-S258. doi: 10.1542/peds.2020-023523H. Pediatrics. 2021. PMID: 33386327
-
Impact of co-occurring substance use on 6 month outcomes for young people seeking mental health treatment.Aust N Z J Psychiatry. 2007 Nov;41(11):896-902. doi: 10.1080/00048670701634986. Aust N Z J Psychiatry. 2007. PMID: 17924242
-
Using NIATx strategies to implement integrated services in routine care: a study protocol.BMC Health Serv Res. 2018 Jun 8;18(1):431. doi: 10.1186/s12913-018-3241-4. BMC Health Serv Res. 2018. PMID: 29884164 Free PMC article.
-
Integrated treatment of co-occurring mental illness and addiction: clinical intervention, program, and system perspectives.CNS Spectr. 2004 Dec;9(12):892-904, 925. doi: 10.1017/s1092852900009718. CNS Spectr. 2004. PMID: 15618940 Review.
Cited by
-
Addressing adolescent substance use in an urban pediatric federally qualified health center.J Subst Abuse Treat. 2022 Apr;135:108653. doi: 10.1016/j.jsat.2021.108653. Epub 2021 Oct 28. J Subst Abuse Treat. 2022. PMID: 34840042 Free PMC article.
-
Adolescents' Adverse Childhood Experiences, Poor Mental Health, and Substance Use During the COVID-19 Pandemic.J Adolesc Health. 2025 Jan;76(1):52-61. doi: 10.1016/j.jadohealth.2024.07.030. Epub 2024 Sep 28. J Adolesc Health. 2025. PMID: 39352358 Free PMC article.
-
Impact of Co-Occurring Psychiatric Comorbidities and Substance Use Disorders on Outcomes in Adolescents and Young Adults with Opioid Use Disorder: A Retrospective Cohort Study.Pharmaceuticals (Basel). 2025 Apr 23;18(5):609. doi: 10.3390/ph18050609. Pharmaceuticals (Basel). 2025. PMID: 40430432 Free PMC article.
-
Interventions for prevention and treatment of substance use in youth with traumatic childhood experiences: a systematic review and synthesis of the literature.Eur Child Adolesc Psychiatry. 2024 Oct;33(10):3419-3438. doi: 10.1007/s00787-023-02265-x. Epub 2023 Jul 22. Eur Child Adolesc Psychiatry. 2024. PMID: 37480386
-
Development of a brief inpatient curriculum to enhance trainee skills in assessment and treatment of adolescents with substance use and co-occurring mental health problems.Int J Psychiatr Trainees. 2025;3(1):10.55922/001c.94859. doi: 10.55922/001c.94859. Epub 2024 Mar 15. Int J Psychiatr Trainees. 2025. PMID: 40547215 Free PMC article.
References
-
- Center for Behavioral Health Statistics and Quality. 2017 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD; 2018. Available at: https://www.samhsa.gov/data/nsduh/reports-detailed-tables-2017-NSDUH. Accessed November 18, 2019
-
- White AM, Jordan JD, Schroeder KM, et al. Predictors of relapse during treatment and treatment completion among marijuana-dependent adolescents in an intensive outpatient substance abuse program. Subst Abus. 2004;25(1):53–59 - PubMed
-
- Reavley NJ, Cvetkovski S, Jorm AF, Lubman DI. Help-seeking for substance use, anxiety and affective disorders among young people: results from the 2007 Australian National Survey of Mental Health and Wellbeing. Aust N Z J Psychiatry. 2010;44(8):729–735 - PubMed
-
- Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62(6):593–602 - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical