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Comment
. 2021 Apr;160(5):1891-1893.
doi: 10.1053/j.gastro.2020.05.103. Epub 2020 Dec 30.

Correlation Between Liver Function Tests Abnormalities and Interleukin-6 Serum Levels in Patients With SARS-CoV-2 Infection

Francesca Romana Ponziani  1 , Antonio Nesci  2 , Fabio Del Zompo  3 , Francesco Santopaolo  3 , Maurizio Pompili  3 , Antonio Gasbarrini  3
Affiliations
Comment

Correlation Between Liver Function Tests Abnormalities and Interleukin-6 Serum Levels in Patients With SARS-CoV-2 Infection

Francesca Romana Ponziani et al. Gastroenterology. 2021 Apr.
No abstract available

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Figures

Figure 1
Figure 1
IL-6 median serum levels in patients with abnormal liver tests (upper limit of normal [ULN]: alanine aminotransferase [ALT] 45 IU/L, gamma glutamyl transferase [GGT] 31 IU/L) and in phase 1 (<7 days after symptoms onset) or 2 (>7 or <15 days after symptom onset) patients. Log-transformed data are reported; black bars and boxes indicate median values and interquartile ranges, whiskers the minimum and maximum.
See this image and copyright information in PMC

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  • Reply.
    Singh S, Khan A. Singh S, et al. Gastroenterology. 2021 Apr;160(5):1895-1896. doi: 10.1053/j.gastro.2021.01.015. Epub 2021 Jan 13. Gastroenterology. 2021. PMID: 33453227 Free PMC article. No abstract available.

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  • Reply.
    Singh S, Khan A. Singh S, et al. Gastroenterology. 2021 Apr;160(5):1895-1896. doi: 10.1053/j.gastro.2021.01.015. Epub 2021 Jan 13. Gastroenterology. 2021. PMID: 33453227 Free PMC article. No abstract available.

References

    1. Singh S. Gastroenterology. 2020;159:768–771. - PMC - PubMed
    1. Del Zompo F. Eur Rev Med. Pharmacol Sci. 2020;24:13072–13088. - PubMed
    1. Ponziani F.R. Aliment Pharmacol Ther. 2020;52:1060–1068. - PMC - PubMed
    1. Hamming I. J Pathol. 2004;203:631–637. - PMC - PubMed
    1. Chai X. BioRxiv. 2020;2020 02.03.931766.