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. 1988 Feb;78(2):179-82.
doi: 10.1007/BF00278192.

Investigation of three XX males by cytogenetic and DNA analyses. Suggestion of Y chromosome inversion polymorphism

K B Nielsen  1 , M Schwartz, H Sardemann
Affiliations

Investigation of three XX males by cytogenetic and DNA analyses. Suggestion of Y chromosome inversion polymorphism

K B Nielsen et al. Hum Genet. 1988 Feb.

Abstract

We report cytogenetic and DNA studies in three XX males. Two males seemed to have extra chromosomal material on the tip of one X chromosome. All three males were shown to have Y chromosome material as indicated by hybridization of Y-specific DNA probes to genomic DNA. One male was unusual in that as he showed the 15-kb fragment detected by pDP34 that is thought to map close to the Y centromere. It is suggested that this finding might point to an inversion on the Y chromosome.

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References

    1. EMBO J. 1985 Jul;4(7):1739-43 - PubMed
    1. Am J Hum Genet. 1986 Feb;38(2):109-24 - PubMed
    1. Lancet. 1966 Aug 27;2(7461):475-6 - PubMed
    1. Hum Genet. 1979 May 23;49(1):11-31 - PubMed
    1. Science. 1986 Aug 15;233(4765):786-8 - PubMed