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Comment
. 2021 Mar;147(3):1117.
doi: 10.1016/j.jaci.2020.11.018. Epub 2020 Dec 30.

Inhaled corticosteroids and angiotensin-converting enzyme-2 in COPD

Brian Lipworth  1 , Rory Chan  2 , Chris Kuo  2
Affiliations
Comment

Inhaled corticosteroids and angiotensin-converting enzyme-2 in COPD

Brian Lipworth et al. J Allergy Clin Immunol. 2021 Mar.
No abstract available

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  • Reply.
    Farne H, Singanayagam A. Farne H, et al. J Allergy Clin Immunol. 2021 Mar;147(3):1117-1118. doi: 10.1016/j.jaci.2020.11.019. Epub 2020 Dec 30. J Allergy Clin Immunol. 2021. PMID: 33388170 Free PMC article. No abstract available.

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References

    1. Finney LJ, Glanville N, Farne H, Aniscenko J, Fenwick P, Kemp SV, et al. Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon [published online ahead of print October 15, 2020]. J Allergy Clin Immunol. https://doi.org/10.1016/j.jaci.2020.09.034. - DOI - PMC - PubMed
    1. Schultze A., Walker A.J., MacKenna B., Morton C.E., Bhaskaran K., Brown J.P., et al. Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform. Lancet Respir Med. 2020;8:1106–1120. - PMC - PubMed
    1. Singanayagam A, Johnston SL. Long-term impact of inhaled corticosteroid use in asthma and chronic obstructive pulmonary disease (COPD): review of mechanisms that underlie risks [published online ahead of print January 14, 2020]. J Allergy Clin Immunol. https://doi.org/10.1016/j.jaci.2019.12.907. - DOI - PubMed

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