A narrative review of HPV vaccination interventions in rural U.S. communities

doi:10.1016/j.ypmed.2020.106407

. 2021 Apr:145:106407.

doi: 10.1016/j.ypmed.2020.106407. Epub 2021 Jan 1.

A narrative review of HPV vaccination interventions in rural U.S. communities

Heather M Brandt¹, Robin C Vanderpool², Meagan Pilar³, Maria Zubizarreta⁴, Lindsay R Stradtman⁵

Affiliations

¹ University of South Carolina Arnold School of Public Health, Department of Health Promotion, Education, Behavior, Rural and Minority Health Research Center, 915 Greene Street, Columbia, SC 29208, United States. Electronic address: hbrandt@sc.edu.
² National Cancer Institute, Division of Cancer Control and Population Sciences, Health Communication and Informatics Research Branch, 9609 Medical Center Drive, 3E610, Rockville, MD 20850, United States. Electronic address: robin.vanderpool@nih.gov.
³ Washington University in St. Louis, Brown School of Social Work, One Brookings Drive, Campus Box 1196, St. Louis, MO 63130, United States. Electronic address: meagan.pilar@wustl.edu.
⁴ University of South Carolina Arnold School of Public Health, Core for Applied Research and Evaluation, 915 Greene Street, Columbia, SC 29208, United States. Electronic address: zubizarr@mailbox.sc.edu.
⁵ University of Kentucky College of Public Health, Department of Health, Behavior & Society, 113 Washington Avenue, Lexington, KY 40506, United States.

PMID: 33388323
PMCID: PMC10064483
DOI: 10.1016/j.ypmed.2020.106407

A narrative review of HPV vaccination interventions in rural U.S. communities

Heather M Brandt et al. Prev Med. 2021 Apr.

. 2021 Apr:145:106407.

doi: 10.1016/j.ypmed.2020.106407. Epub 2021 Jan 1.

Authors

Heather M Brandt¹, Robin C Vanderpool², Meagan Pilar³, Maria Zubizarreta⁴, Lindsay R Stradtman⁵

Affiliations

¹ University of South Carolina Arnold School of Public Health, Department of Health Promotion, Education, Behavior, Rural and Minority Health Research Center, 915 Greene Street, Columbia, SC 29208, United States. Electronic address: hbrandt@sc.edu.
² National Cancer Institute, Division of Cancer Control and Population Sciences, Health Communication and Informatics Research Branch, 9609 Medical Center Drive, 3E610, Rockville, MD 20850, United States. Electronic address: robin.vanderpool@nih.gov.
³ Washington University in St. Louis, Brown School of Social Work, One Brookings Drive, Campus Box 1196, St. Louis, MO 63130, United States. Electronic address: meagan.pilar@wustl.edu.
⁴ University of South Carolina Arnold School of Public Health, Core for Applied Research and Evaluation, 915 Greene Street, Columbia, SC 29208, United States. Electronic address: zubizarr@mailbox.sc.edu.
⁵ University of Kentucky College of Public Health, Department of Health, Behavior & Society, 113 Washington Avenue, Lexington, KY 40506, United States.

PMID: 33388323
PMCID: PMC10064483
DOI: 10.1016/j.ypmed.2020.106407

Abstract

Uptake of human papillomavirus (HPV) vaccine in the United States (U.S.) is far below the Healthy People 2020 goal of 80% coverage among adolescents. In rural communities, HPV vaccination coverage is low, yet incidence and mortality rates of HPV-associated cancer are high. Much of the research focused on HPV vaccination in rural U.S. communities has involved qualitative investigations, observations, survey research, and secondary data analysis with limited implementation of interventional study designs. The purpose of this narrative review was to examine intervention studies to increase HPV vaccination in rural settings and to summarize study characteristics and associated outcomes. PubMed, PsycINFO, CINAHL, and Web of Science were searched utilizing systematic narrative review methodology for studies describing implementation of HPV vaccination interventions in rural U.S. settings from January 2006-December 2019. Using specific search criteria, 991 studies were identified. After abstract review, 30 full-text articles were assessed for eligibility, and 15 met the inclusion criteria. The 15 articles - published from 2011 to 2019 - described HPV vaccination interventions in rural settings of six states, including communities, health clinics, and schools. A range of primary and secondary outcomes were reported, including HPV vaccine receipt (series initiation, continuation, and/or completion); HPV vaccine knowledge; and/or cervical cancer knowledge. Across the studies, there was an absence of the description of rural context. As compared to the broader HPV vaccination intervention literature, interventions in rural settings were limited. More interventional research is needed in rural communities given the elevated rates of HPV-related cancer and low rates of HPV vaccine uptake.

Keywords: Neoplasms; Papillomavirus vaccines; Rural populations; United States; Vaccination.

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Conflict of interest statement

The authors have no conflicts of interest to report.

Figures

**Figure 1:**
PRISMA flow chart of the narrative review process

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References

1. American Hospital Association, 2019. Challenges facing rural communities and the roadmap to ensure local access to high-quality, affordable care. Chicago (IL).
1. Appalachian Regional Commission, 2018. Exploring bright spots in Appalachian health: Case studies. Washington (DC).
1. Barefoot KN, Warren JC, Smalley KB, 2017. Women’s health care: the experiences and behaviors of rural and urban lesbians in the USA. Rural Remote Health 17, 3875. 10.22605/rrh3875 - DOI - PubMed
1. Bednarczyk RA, Whitehead JL, Stephenson R, 2017. Moving beyond sex: Assessing the impact of gender identity on human papillomavirus vaccine recommendations and uptake among a national sample of rural-residing LGBT young adults. Papillomavirus Res. 3, 121–125. 10.1016/j.pvr.2017.04.002 - DOI - PMC - PubMed
1. Bhatta MP, Phillips L, 2015. Human papillomavirus vaccine awareness, uptake, and parental and health care provider communication among 11- to 18-year-old adolescents in a rural Appalachian Ohio county in the United States. J. Rural Heal 31, 67–75. 10.1111/jrh.12079 - DOI - PubMed

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[1] American Hospital Association, 2019. Challenges facing rural communities and the roadmap to ensure local access to high-quality, affordable care. Chicago (IL).

[2] American Hospital Association, 2019. Challenges facing rural communities and the roadmap to ensure local access to high-quality, affordable care. Chicago (IL).

[3] Appalachian Regional Commission, 2018. Exploring bright spots in Appalachian health: Case studies. Washington (DC).

[4] Appalachian Regional Commission, 2018. Exploring bright spots in Appalachian health: Case studies. Washington (DC).

[5] Barefoot KN, Warren JC, Smalley KB, 2017. Women’s health care: the experiences and behaviors of rural and urban lesbians in the USA. Rural Remote Health 17, 3875. 10.22605/rrh3875 - DOI - PubMed

[6] Barefoot KN, Warren JC, Smalley KB, 2017. Women’s health care: the experiences and behaviors of rural and urban lesbians in the USA. Rural Remote Health 17, 3875. 10.22605/rrh3875 - DOI - PubMed

[7] Bednarczyk RA, Whitehead JL, Stephenson R, 2017. Moving beyond sex: Assessing the impact of gender identity on human papillomavirus vaccine recommendations and uptake among a national sample of rural-residing LGBT young adults. Papillomavirus Res. 3, 121–125. 10.1016/j.pvr.2017.04.002 - DOI - PMC - PubMed

[8] Bednarczyk RA, Whitehead JL, Stephenson R, 2017. Moving beyond sex: Assessing the impact of gender identity on human papillomavirus vaccine recommendations and uptake among a national sample of rural-residing LGBT young adults. Papillomavirus Res. 3, 121–125. 10.1016/j.pvr.2017.04.002 - DOI - PMC - PubMed

[9] Bhatta MP, Phillips L, 2015. Human papillomavirus vaccine awareness, uptake, and parental and health care provider communication among 11- to 18-year-old adolescents in a rural Appalachian Ohio county in the United States. J. Rural Heal 31, 67–75. 10.1111/jrh.12079 - DOI - PubMed

[10] Bhatta MP, Phillips L, 2015. Human papillomavirus vaccine awareness, uptake, and parental and health care provider communication among 11- to 18-year-old adolescents in a rural Appalachian Ohio county in the United States. J. Rural Heal 31, 67–75. 10.1111/jrh.12079 - DOI - PubMed

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A narrative review of HPV vaccination interventions in rural U.S. communities

Affiliations

A narrative review of HPV vaccination interventions in rural U.S. communities

Authors

Affiliations

Abstract

Conflict of interest statement

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References

Publication types

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Medical

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Miscellaneous