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Review
. 2021 Mar;24(1):216-233.
doi: 10.1007/s10729-020-09534-0. Epub 2021 Jan 3.

A simulation-based approach for improving the clinical blood sample supply chain

Amir Elalouf  1 , Dmitry Tsadikovich  2 , Sharon Hovav  3
Affiliations
Review

A simulation-based approach for improving the clinical blood sample supply chain

Amir Elalouf et al. Health Care Manag Sci. 2021 Mar.

Abstract

We consider a three-echelon blood sample supply chain comprising the following elements: (i) clinics, where blood samples are taken from patients, (ii) centrifugation centers, where collected blood samples are separated into their different components, and (iii) a centralized testing laboratory, where the samples are analyzed. We focus on the scheduling of vehicles that transport blood samples from clinics to centrifugation centers-a special case of the vehicle routing problem (VRP). Our study presents a novel simulation-based approach to the VRP, designed and implemented in MATLAB, and tailored to the unique constraints of the three-echelon blood sample collection chain. We apply this approach to data from a large Health Maintenance Organization to determine the optimal vehicle fleet size for blood sample transport, while ensuring that the quality of the healthcare service is not compromised. Results suggest that our simulation model can be generalized to serve as a useful and straightforward decision support tool for optimizing resource utilization and service quality in healthcare systems.

Keywords: Blood samples collection; Discrete event simulation; Healthcare supply chain; Operations research; Transportation.

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References

    1. Revere L (2004) Re-engineering proves effective for reducing courier costs. Bus Process Manag J 10(4):400–414 - DOI
    1. Yücel E, Salman FS, Gel ES, Örmeci EL, Gel A (2013) Optimizing specimen collection for processing in clinical testing laboratories. Eur J Oper Res 227(3):503–514 - DOI
    1. Grasas A, Ramalhinho H, Pessoa LS, Resende MGC, Caballé I, Barba N (2014) On the improvement of blood sample collection at clinical laboratories. BMC Health Serv Res 14(1):12 - DOI
    1. Elalouf A, Hovav S, Tsadikovich D, Yedidsion L (2015) Minimizing operational costs by restructuring the blood sample collection chain. Oper Res Heal Care 7:81–93 - DOI
    1. Elalouf A, Tsadikovich D, Hovav S (2016) Optimization of blood sample collection with timing and quality constraints. Int Trans Oper Res 25(1):191–214 - DOI

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