Trends in the Incidence, Prevalence, and Mortality of End-Stage Kidney Disease in South Korea

Abstract

Knowledge of the epidemiologic characteristics of end-stage kidney disease (ESKD) patients is essential. The trends in the prevalence, incidence, and mortality rates of ESKD were analyzed retrospectively using the Korean National Health Insurance ServiceNational Sample Cohort database between 2006 and 2015. From 2006 to 2015, the incidence of ESKD decreased from 28.6 to 24.0 per 100,000 people and showed a decreasing pattern with or without diabetes mellitus. However, the incidence of those aged ≥75 years increased, as did the mean age at the onset of ESKD. From 2007 to 2015, the prevalence of ESKD increased in all age groups, but particularly in those aged ≥75 years. The prevalence of ESKD differed by sex and diabetes mellitus status and this gap widened over time. Mortality rates in ESKD patients remained relatively constant throughout the study period. However, mortality rates in ESKD without diabetes decreased over the same period.

Keywords: Diabetes mellitus; Incidence; Kidney failure, chronic; Mortality; Prevalence.

Fig. 1

Incidence, prevalence, mortality rates of end-stage kidney disease in South Korea, 2006 to 2015 by age group, sex, and diabetes mellitus status. (A) Incidence rate by age group. (B) Incidence rate by sex. (C) Incidence rate by diabetes mellitus status. (D) Prevalence rate by age group. (E) Prevalence rate by sex. (F) Prevalence rate by diabetes mellitus status. (G) Mortality rate by age group. (H) Mortality rate by sex. (I) Mortality rate by diabetes mellitus status. (A, D, G) ‘All ages’ are shown as standardized values, and the remaining subdivided age groups are shown as crude values.

Fig. 2

The most common causes of death as proportions of all deaths in end-stage kidney disease patients (A), in end-stage kidney disease patients with diabetes mellitus (B), and in end-stage kidney disease patients without diabetes mellitus (C) during 2007 to 2015.