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. 2020 Dec;12(4):281-284.
doi: 10.1055/s-0040-1721149. Epub 2020 Dec 30.

Challenging Presentations of Seven Cases of Gastrointestinal Basidiobolomycosis in Sudan: Clinical Features, Histology, Imaging, and Recommendations

Sawsan A Mohammed  1 , Azza A Abdelsatir  2 , Mohamed Abdellatif  3 , Suliman Hussein Suliman  4 , Omer Mohammed Ibrahim Elbasheer  5 , Awad Rhmattalla Abdalla  4 , Abubakr H Widattalla  4 , Safeya Ahmed M Tamimeldar  6 , Abdelgadir A Amin  7 , Mohamed H Ahmed  8 , Ali Mohammed Abdelsatir  2
Affiliations

Challenging Presentations of Seven Cases of Gastrointestinal Basidiobolomycosis in Sudan: Clinical Features, Histology, Imaging, and Recommendations

Sawsan A Mohammed et al. J Lab Physicians. 2020 Dec.

Abstract

Basidiobolomycosis is a fungal infection caused by Basidiobolus ranarum which affects the skin and subcutaneous tissue and rarely the gastrointestinal tract. We report seven cases of gastrointestinal basidiobolomycosis with interesting clinical, radiological, and histological presentations. To our knowledge, this is the first case series of abdominal basidiobolomycosis to be reported from Sudan.

Keywords: Sudan; basidiobolomycosis; gastrointestinal.

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Conflict of interest statement

Conflict of Interest None declared.

Figures

Fig. 1
Fig. 1
Computed tomography (CT) abdomen shows diffuse circumferential wall thickening of the right (RT) colon and cecum with surrounding fat stranding.
Fig. 2
Fig. 2
Gross morphology showed thick bowel wall with stenotic mass.
Fig. 3
Fig. 3
Histology of the resected bowel shows broad fungal hyphae surrounded by marked eosinophil infiltrate and giant cells. Splendore–Hoeppli reaction is noted. Hematoxylin and eosin (H&E) ×40.
Fig. 4
Fig. 4
Left: Periodic acid-Schiff (PAS) stain. Right: Grocott-Gomori’s Methenamine Silver (GMS) stain both highlight the broad fungal hyphae.
See this image and copyright information in PMC

References

    1. Al-Qahtani S M, Alsuheel A M, Shati A A et al.Case reports: gastrointestinal basidiobolomycosis in children. Curr Pediatr Res. 2013;17(01):1–6.
    1. Vikram H R, Smilack J D, Leighton J A, Crowell M D, De Petris G. Emergence of gastrointestinal basidiobolomycosis in the United States, with a review of worldwide cases. Clin Infect Dis. 2012;54(12):1685–1691. - PubMed
    1. Al A smi MM, Faqeehi H Y, Alshahrani D A, Al-Hussaini A A. A case of pediatric gastrointestinal basidiobolomycosis mimicking Crohn’s disease. A review of pediatric literature. Saudi Med J. 2013;34(10):1068–1072. - PubMed
    1. Almoosa Z, Alsuhaibani M, Al Dandan S, Alshahrani D. Pediatric gastrointestinal basidiobolomycosis mimicking malignancy. Med Mycol Case Rep. 2017;18:31–33. - PMC - PubMed
    1. Geramizadeh B, Heidari M, Shekarkhar G. Gastrointestinal basidiobolomycosis, a rare and under-diagnosed fungal infection in immunocompetent hosts: a review article. Iran J Med Sci. 2015;40(02):90–97. - PMC - PubMed