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. 2021 May;135(3):787-790.
doi: 10.1007/s00414-020-02498-4. Epub 2021 Jan 3.

Exploring the Western Mediterranean through X-chromosome

J F Ferragut  1 , K Bentayebi  2 , A Barbaro  3 , M Ramírez  1 , A Y Saguillo  1 , C Ramon  1 , A Picornell  4
Affiliations

Exploring the Western Mediterranean through X-chromosome

J F Ferragut et al. Int J Legal Med. 2021 May.

Abstract

In this study, we investigate the forensic and population genetics properties of 21 X-chromosome markers (9 X-Alu insertions and 12 X-STRs) in a dataset composed of 716 individuals from 11 Western Mediterranean populations. The high values of combined forensic parameters indicate that this 21 X-loci panel can complement autosomal or uniparental markers in kinship analysis and complex deficient paternity testing in the populations studied. Population analyses revealed a lower differentiation between Western Mediterranean human groups for X-STRs than for X-Alu insertion polymorphisms. Moreover, X-chromosome markers suggest a sex-biased migration rate, confirming the predominance of patrilocality in this area.

Keywords: Alu insertions; Balearic Islands; Calabria; Investigator Argus X-12 kit; Morocco; Valencia; Western Mediterranean; X-STR; X-chromosome.

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