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. 2021 Mar;38(2):502-503.
doi: 10.1111/pde.14492. Epub 2021 Jan 3.

Assessing vaccination reactions in pediatric patients with maculopapular cutaneous mastocytosis

Maija L Johansen  1 , Leslie P Lawley  1
Affiliations

Assessing vaccination reactions in pediatric patients with maculopapular cutaneous mastocytosis

Maija L Johansen et al. Pediatr Dermatol. 2021 Mar.

Abstract

Immunization compliance in the United States is declining, in part due to misinformation and fear surrounding adverse vaccination reactions. Recently, there have been data published in the allergy and immunology literature to show that there may be a relationship between routine vaccinations and induction of symptoms in cutaneous mastocytosis patients; however, this has not yet been explored in the dermatology literature. We sought to uncover the prevalence of vaccine reactions due to mast cell activation within our cohort of maculopapular cutaneous mastocytosis (MPCM) patients in order to contribute to ensuring administration safety, managing familial expectations, and encouraging continued adherence. Our results indicate that while incidence of reaction rates may be higher than the national average, they are mild and families should be counseled to follow recommended immunization schedule guidelines.

Keywords: immunizations; maculopapular cutaneous mastocytosis; mastocytosis; pediatrics; urticaria pigmentosa; vaccination reactions.

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References

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