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Comment
. 2021 Apr;174(4):558-559.
doi: 10.7326/M20-8280. Epub 2021 Jan 5.

U.S. COVID-19 Vaccination Challenges Go Beyond Supply

Thomas J Bollyky  1
Affiliations
Comment

U.S. COVID-19 Vaccination Challenges Go Beyond Supply

Thomas J Bollyky. Ann Intern Med. 2021 Apr.

Abstract

Currently in Annals, a trio of articles each takes a different route to the same conclusion: Using initial supplies of COVID-19 vaccines to immunize as many persons as possible with a single-dose regimen may achieve more benefit than reserving supplies to administer a more effective 2-dose regimen to a smaller population. The editorialist discusses factors that may impede the timely vaccination of a substantial proportion of the U.S. population and the circumstances under which the ideas posited by the 3 articles for stretching vaccine supplies may have the greatest utility.

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Conflict of interest statement

Disclosures: Author has disclosed no conflicts of interest. Form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M20-8280.

Comment on

References

    1. Paltiel DA, Zheng A, Schwartz JL, et al. Speed versus efficacy: quantifying potential tradeoffs in COVID-19 vaccine deployment. Ann Intern Med. 5 January 2021. [Epub ahead of print]. doi:10.7326/M20-7866 - PMC - PubMed
    1. Barnabas RV, Wald A. A public health COVID-19 vaccine strategy to maximize the health gains for every single vaccine dose. Ann Intern Med. 5 January 2021. [Epub ahead of print]. doi:10.7326/M20-8060 - PMC - PubMed
    1. Tuite AR, Zhu L, Fisman DN, Salomon JA. Alternative dose allocation strategies to increase benefits from constrained COVID-19 vaccine supply. Ann Intern Med. 5 January 2021. [Epub ahead of print]. doi:10.7326/M20-8137 - PMC - PubMed
    1. U.S. Centers for Disease Control and Prevention. Influenza (Flu): Influenza Vaccination Coverage. Accessed at www.cdc.gov/flu/fluvaxview/index.htm on 30 December 2020.
    1. U.S. Centers for Disease Control and Prevention. Influenza (Flu): Final estimates for 2009–10 Seasonal Influenza and Influenza A (H1N1) 2009 Monovalent Vaccination Coverage – United States, August 2009 through May, 2010. Accessed at www.cdc.gov/flu/fluvaxview/coverage_0910estimates.htm on 30 December 2020.

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