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Case Reports
. 2021 Jan 8;50(1):63-65.
doi: 10.3760/cma.j.cn112151-20200522-00403.

[Fibrocartilaginous mesenchymoma: report of a case]

[Article in Chinese]
Affiliations
Case Reports

[Fibrocartilaginous mesenchymoma: report of a case]

[Article in Chinese]
R F Dong et al. Zhonghua Bing Li Xue Za Zhi. .

Abstract

纤维软骨性间叶瘤(fibrocartilagenous mesenchymoma, FM)是一种罕见的骨内原发性交界性肿瘤。本文报道1例13岁男性,L3椎体肿物,组织形态学显示具有轻度不典型性的梭形细胞密集增生,软骨呈团巢状散在分布,部分似骺板样结构,局部有不规则新生骨形成。免疫组织化学结果:平滑肌肌动蛋白、S-100蛋白、结蛋白、CD34、上皮细胞膜抗原、p16及p53等均阴性,Ki-67阳性指数约2%。分子表型:GNAS、IDH1和IDH2基因无突变,MDM2基因无扩增。患者术后108个月无复发及转移。诊断时应着重与纤维软骨性结构不良、去分化软骨肉瘤及低级别中心性骨肉瘤等鉴别。.

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