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Case Reports
. 2021 Feb;27(2):384-386.
doi: 10.1016/j.jiac.2020.11.016. Epub 2020 Dec 23.

Immunochromatographic test for the detection of SARS-CoV-2 in saliva

Katsuhito Kashiwagi  1 , Yoshikazu Ishii  2 , Kotaro Aoki  2 , Shintaro Yagi  3 , Tadashi Maeda  1 , Taito Miyazaki  1 , Sadako Yoshizawa  4 , Katsumi Aoyagi  5 , Kazuhiro Tateda  2
Affiliations
Case Reports

Immunochromatographic test for the detection of SARS-CoV-2 in saliva

Katsuhito Kashiwagi et al. J Infect Chemother. 2021 Feb.

Abstract

We evaluated the rapid immunochromatographic test for severe acute respiratory coronavirus 2 (SARS-CoV-2) antigen detection using 16 saliva specimens collected from 6 COVID-19 hospitalized patients, and detected N-antigen in 4 of 7 RT-PCR positive specimens. This POCT detected SARS-CoV-2 antigen in saliva and would be useful for COVID-19 diagnosis.

Keywords: Antigen test; COVID-19; Immunochromatography; POCT; SARS-CoV-2.

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Conflict of interest statement

Declaration of competing interest SY is an employee and KaA is the director of Fujirebio Inc.

Figures

Fig. 1
Fig. 1
Detection of SARS-CoV-2 N antigen in nasopharyngeal swab and saliva specimens. N antigen-positive specimens are shown as solid circles; negative specimens are shown as open circles. Crosses indicate specimens that were not assayed by the antigen test. There were 4.525 in antigen-positive and 3.444 and log10 mean RNA copies/mL antigen-negative specimens were, and the difference was not significant (p = 0.1088, t-test).
See this image and copyright information in PMC

Comment in

References

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