Significance of single-cell and spatial transcriptomes in cell biology and toxicology
- PMID: 33398619
- DOI: 10.1007/s10565-020-09576-8
Significance of single-cell and spatial transcriptomes in cell biology and toxicology
References
-
- Aoki T, Chong LC, Takata K, Milne K, Hav M, Colombo A, et al. Single-cell transcriptome analysis reveals disease-defining T-cell subsets in the tumor microenvironment of classic Hodgkin lymphoma. Cancer Discov. 2020;10(3):406–21. https://doi.org/10.1158/2159-8290.CD-19-0680 . - DOI - PubMed
-
- Baccin C, Al-Sabah J, Velten L, Helbling PM, Grünschläger F, Hernández-Malmierca P, et al. Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization. Nat Cell Biol. 2020;22(1):38–48. https://doi.org/10.1038/s41556-019-0439-6 . - DOI - PubMed
-
- Chen J, Suo S, Tam PP, Han JJ, Peng G, Jing N. Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq. Nat Protoc. 2017;12(3):566–80. https://doi.org/10.1038/nprot.2017.003 . - DOI - PubMed
-
- McFaline-Figueroa JL, Hill AJ, Qiu X, Jackson D, Shendure J, Trapnell C. A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition. Nat Genet. 2019;51(9):1389–98. https://doi.org/10.1038/s41588-019-0489-5 . - DOI - PubMed - PMC
-
- Peng G, Cui G, Ke J, Jing N. Using single-cell and spatial transcriptomes to understand stem cell lineage specification during early embryo development. Annu Rev Genomics Hum Genet. 2020;21:163–81. https://doi.org/10.1146/annurev-genom-120219-083220 . - DOI - PubMed
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