Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar;298(3):E152-E155.
doi: 10.1148/radiol.2020203776. Epub 2021 Jan 5.

COVID-19 Diagnosis in Case of Two Negative Nasopharyngeal Swabs: Association between Chest CT and Bronchoalveolar Lavage Results

Filippo Patrucco  1 , Alessandro Carriero  1 , Zeno Falaschi  1 , Alessio Paschè  1 , Francesco Gavelli  1 , Chiara Airoldi  1 , Mattia Bellan  1 , Pier Paolo Sainaghi  1 , Paolo Solidoro #  1 , Piero E Balbo #  1
Affiliations

COVID-19 Diagnosis in Case of Two Negative Nasopharyngeal Swabs: Association between Chest CT and Bronchoalveolar Lavage Results

Filippo Patrucco et al. Radiology. 2021 Mar.

Abstract

See also the editorial by Little in this issue.

PubMed Disclaimer

Figures

Images show chest CT features of patients with true-positive and false-positive results. A, In a 60-year-old man with bilateral diffuse areas of consolidation associated with ground-glass opacity (GGO), chest CT was classified as coronavirus disease 2019 (COVID-19) Reporting and Data System (CO-RADS) category 5 and as typical with Society of Thoracic Radiology/Radiological Society of North America (STR/RSNA) probability score, with subsequent confirmed diagnosis of COVID-19 based on fluid obtained at bronchoalveolar lavage (BAL). B, In a 54-year-old man with bilateral peripheral patchy areas of GGO who was hospitalized but not treated for COVID-19, an alternative diagnosis of viral pneumonia due to metapneumovirus was determined after BAL. Chest CT was classified as CO-RADS category 4 and as indeterminate with STR/RSNA probability score.
Images show chest CT features of patients with true-positive and false-positive results. A, In a 60-year-old man with bilateral diffuse areas of consolidation associated with ground-glass opacity (GGO), chest CT was classified as coronavirus disease 2019 (COVID-19) Reporting and Data System (CO-RADS) category 5 and as typical with Society of Thoracic Radiology/Radiological Society of North America (STR/RSNA) probability score, with subsequent confirmed diagnosis of COVID-19 based on fluid obtained at bronchoalveolar lavage (BAL). B, In a 54-year-old man with bilateral peripheral patchy areas of GGO who was hospitalized but not treated for COVID-19, an alternative diagnosis of viral pneumonia due to metapneumovirus was determined after BAL. Chest CT was classified as CO-RADS category 4 and as indeterminate with STR/RSNA probability score.
See this image and copyright information in PMC

Comment in

References

    1. Corman VM, Landt O, Kaiser M, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill 2020;25(3):2000045. - PMC - PubMed
    1. Prokop M, van Everdingen W, van Rees Vellinga T, et al. CO-RADS: A Categorical CT Assessment Scheme for Patients Suspected of Having COVID-19-Definition and Evaluation. Radiology 2020;296(2):E97–E104. - PMC - PubMed
    1. Simpson S, Kay FU, Abbara S, et al. Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA - Secondary Publication. J Thorac Imaging 2020;35(4):219–227. - PMC - PubMed
    1. Falaschi Z, Danna PSC, Arioli R, et al. Chest CT accuracy in diagnosing COVID-19 during the peak of the Italian epidemic: A retrospective correlation with RT-PCR testing and analysis of discordant cases. Eur J Radiol 2020;130:109192. - PMC - PubMed
    1. Ciccarese F, Coppola F, Spinelli D, et al. Diagnostic Accuracy of North America Expert Consensus Statement on Reporting CT Findings in Patients with Suspected COVID-19 Infection: An Italian Single Center Experience. Radiol Cardiothorac Imaging 2020;2(4):e200312. - PMC - PubMed