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Review
. 2021 Jan 3;26(1):209.
doi: 10.3390/molecules26010209.

Recent Advances in Metal Organic Frameworks Based Surface Enhanced Raman Scattering Substrates: Synthesis and Applications

Panxue Wang  1 , Yan Sun  1 , Xiang Li  1 , Li Wang  1 , Ying Xu  1 , Guoliang Li  1
Affiliations
Review

Recent Advances in Metal Organic Frameworks Based Surface Enhanced Raman Scattering Substrates: Synthesis and Applications

Panxue Wang et al. Molecules. .

Abstract

Metal-organic frameworks (MOFs) are supramolecular nanomaterials, in which metal ions or clusters are connected by organic ligands to form crystalline lattices with highly ordered periodic porous network structure. MOFs have been widely applied in various fields, such as catalyst, sample preparation, and sensing. In recent years, MOFs based surface enhanced Raman scattering (SERS) substrates have attracted much attention since MOFs can largely improve the performance of metallic SERS substrates toward target enrichment and signal enhancement. MOFs have been exploited in SERS analysis to tackle some challenges that bare metal substrates cannot achieve. Combination of MOFs and SERS improved the sensitivity of traditional SERS analysis and extended the application scope of SERS. With the increasing exploration of MOFs based SERS substrates, there is a great demand to review the advances in these researches. Herein, this review concentrated on summarizing the preparation and applications of MOFs based SERS substrates. Representative researches were discussed to better understand the property of MOFs based SERS substrates. The advantages of MOFs based SERS substrates were highlighted, as well as their limitations. In addition, the challenges, opportunities, and future trends in MOFs based SERS analysis were tentatively discussed.

Keywords: applications; delivery; environment field; food filed; metal-organic frameworks; metallic nanoparticles; nano-composites.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 1
Figure 1
Schematic illustration of the synthesis and applications of MOFs based SERS substrates.
See this image and copyright information in PMC

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