Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts
- PMID: 3340187
- DOI: 10.1038/331410a0
Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts
Abstract
Regulation of transcription during development has been analysed in vitro using extracts derived from Drosophila embryos. Transcription of mutant templates reveals cis-control regions of the alcohol dehydrogenase promoter responsible for temporal regulation. The activity of a trans-acting protein correlates with the profile of alcohol dehydrogenase expression during embryogenesis.
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