Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Feb;38(2):185-90.
doi: 10.1212/wnl.38.2.185.

Risk of developing multiple sclerosis after uncomplicated optic neuritis: a long-term prospective study

J F Rizzo 3rd  1 , S Lessell
Affiliations

Risk of developing multiple sclerosis after uncomplicated optic neuritis: a long-term prospective study

J F Rizzo 3rd et al. Neurology. 1988 Feb.

Abstract

We prospectively studied 60 white patients living in New England who presented with uncomplicated optic neuritis (ON) to determine the risk of developing multiple sclerosis (MS). The diagnoses of ON and MS were made solely on the basis of clinical criteria. Patients were followed for a mean of 14.9 years. Life table analysis indicated that 74% of the women and 34% of the men will have developed MS 15 years after their attack of ON. The risk of developing MS was 3.4 times greater for women than for men. Onset of ON between the ages of 21 and 40 years may have had a modest effect in increasing the risk of developing MS. Recurrence of ON did not appear to affect the risk.

PubMed Disclaimer

LinkOut - more resources