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Review
. 2021 Mar;36(3):1062-1066.
doi: 10.1111/jocs.15303. Epub 2021 Jan 6.

Valvular complications following the Impella device implantation

Davorin Sef  1 , Tito Kabir  2 , Nicholas James Lees  3 , Ulrich Stock  1
Affiliations
Review

Valvular complications following the Impella device implantation

Davorin Sef et al. J Card Surg. 2021 Mar.

Abstract

Background: Despite clear clinical benefits, there is limited evidence regarding possible complications of the novel mechanical support device Impella. Aortic and mitral valve regurgitation or injury are rare but potential complications following implantation of the Impella device.

Methods: To evaluate valvular complications after the Impella device implantation, we have performed a comprehensive search of literature on multiple sites on this topic.

Results and conclusion: Ten case reports and one observational retrospective study were identified, with a total number of 19 patients identified. This article aims to draw attention to potential periprocedural complications relating to the Impella, in particular iatrogenic aortic and mitral valve injuries. Moreover, we have summarized our recommendations emphasizing the need for careful management and meticulous follow-up of these patients to avoid such potentially devastating complications.

Keywords: aortic valve injury; aortic valve regurgitation; impella; mechanical circulatory support; mitral valve injury; patient safety.

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References

REFERENCES

    1. Lim HS. The effect of Impella cp on cardiopulmonary physiology during venoarterial extracorporeal membrane oxygenation support. Artif Organs. 2017;41(12):1109-1112.
    1. Sabra MJ, Andrews WG, Crandall ML, Pirris JP. The postoperative use of Impella as a ventricular assist device in high-risk patients undergoing coronary artery bypass surgery: a case series and comparison. J Card Surg. 2020;35(1):113-117.
    1. Schibilsky D, Lausberg H, Haller C, et al. Impella 5.0 support in INTERMACS II cardiogenic shock patients using right and left axillary artery access. Artif Organs. 2015;39(8):660-663.
    1. Grajeda Silvestri ER, Pino JE, Donath E, Torres P, Chait R, Ghumman W. Impella to unload the left ventricle in patients undergoing venoarterial extracorporeal membrane oxygenation for cardiogenic shock: a systematic review and meta-analysis. J Card Surg. 2020;35(6):1237-1242.
    1. Madjarov JM, Katz MG, Fazal S, Madzharov S. Mechanical circulatory support with extracorporeal membrane oxygenation and Impella 5.5 in patients with a postinfarction VSD: combined or separate assist strategy? J Card Surg. 2020. https://doi.org/10.1111/jocs.15204

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