Pandemic of the aging society - sporadic cerebral small vessel disease
- PMID: 33410627
- PMCID: PMC7817343
- DOI: 10.1097/CM9.0000000000001320
Pandemic of the aging society - sporadic cerebral small vessel disease
Abstract
Age-related sporadic cerebral small vessel disease (CSVD) has gained increasing attention over the past decades because of its increasing prevalence associated with an aging population. The widespread application of and advances in brain magnetic resonance imaging in recent decades have significantly increased researchers' understanding in the in vivo evolution of CSVD, its impact upon the brain, its risk factors, and the mechanisms that explain the various clinical manifestation associated with sporadic CSVD. In this review, we aimed to provide an update on the pathophysiology, risk factors, biomarkers, and the determinants and spectrum of the clinical manifestation of sporadic CSVD.
Copyright © 2020 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.
Conflict of interest statement
None.
Figures


References
-
- Hilal S, Mok V, Youn YC, Wong A, Ikram MK, Chen CL-H. Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries. J Neurol Neurosurg Psychiatry 2017; 88:669–674. doi: 10.1136/jnnp-2016-315324. - PubMed
-
- Mok V, Srikanth V, Xiong Y, Phan TG, Moran C, Chu S, et al. Race-ethnicity and cerebral small vessel disease – comparison between Chinese and White populations. Int J Stroke 2014; 9:36–42. doi: 10.1111/ijs.12270. - PubMed
-
- Desmond DW, Moroney JT, Sano M, Stern Y. Incidence of dementia after ischemic stroke: results of a longitudinal study. Stroke 2002; 33:2254–2260. doi: 10.1161/01.str.0000028235.91778.95. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous