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. 2021 May;65(3):402-408.
doi: 10.1007/s10384-020-00806-4. Epub 2021 Jan 7.

Comparison of 12-month surgical outcomes of ab interno trabeculotomy with phacoemulsification between spatula-shaped and dual-blade microhooks

Takashi Omoto  1 , Takashi Fujishiro  2 , Kimiko Asano-Shimizu  1 , Koichiro Sugimoto  1 , Rei Sakata  1 , Hiroshi Murata  1 , Ryo Asaoka  1 , Megumi Honjo  1 , Makoto Aihara  1
Affiliations

Comparison of 12-month surgical outcomes of ab interno trabeculotomy with phacoemulsification between spatula-shaped and dual-blade microhooks

Takashi Omoto et al. Jpn J Ophthalmol. 2021 May.

Abstract

Purpose: To compare 12-month clinical results of spatula-shaped and dual-blade microhooks ab interno trabeculotomy with phacoemulsification.

Study design: Retrospective comparative study.

Methods: We conducted a retrospective chart review of Japanese open-angle glaucoma patients who underwent ab interno trabeculotomy with phacoemulsification with a 12-month follow-up. Two types of trabecular hook were used: the spatula-shaped Tanito Trabeculotomy ab interno Micro-hook® and the Kahook Dual Blade®. Changes in intraocular pressure (IOP) and medication scores comprised the main outcome metrics. We also analyzed and compared patient demographics and the occurrence of complications.

Results: Trabeculotomy was performed using a spatula-shaped hook in 17 eyes and a dual-blade hook in 15 eyes. Significant reductions in IOP (p < 0.001) and medication scores (p < 0.001) were noted in both groups after the 1-month time point. The percentage changes of IOP from baseline at each time point were not significantly different between groups, though there was a significant difference in medication scores at 12 months (p = 0.0192). Postoperative complications occurred similarly in both groups; one case in the dual-blade group required additional filtration surgery.

Conclusions: Ab interno trabeculotomy with phacoemulsification was effective in lowering IOP both with spatula-shaped and with double-blade microhooks. At 12 months more medications were used postoperatively in the spatula-shaped microhook group; however, the reductions in the medication scores from baseline were statistically significant in both groups.

Keywords: Glaucoma; Intraocular pressure; MIGS; Trabeculectomy; Trabeculotomy.

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References

    1. Collaborative Normal-Tension Glaucoma Study Group. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Am J Ophthalmol. 1998;126:498–505. - DOI
    1. Collaborative Normal-Tension Glaucoma Study Group. The advanced glaucoma intervention study (AGIS): 7. the relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol. 2000;130:429–40. - DOI
    1. Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M. Early manifest glaucoma trial G: reduction of intraocular pressure and glaucoma progression: results from the early manifest glaucoma trial. Arch Ophthalmol. 2002;120:1268–79. - DOI
    1. Musch DC, Gillespie BW, Niziol LM, Lichter PR, Varma R, Group CS. Intraocular pressure control and long-term visual field loss in the collaborative initial glaucoma treatment study. Ophthalmology. 2011;118:1766–73. - DOI
    1. Inoue K, Ishida K, Tomita G, Noma H. A scoping review and network meta-analysis for efficacy and safety of glaucoma medication in Japanese patients. Jpn J Ophthalmol. 2020;64:103–13. - DOI

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