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. 2021 Jun 3;17(6):1747-1756.
doi: 10.1080/21645515.2020.1844505. Epub 2021 Jan 7.

A systematic review of the burden of pertussis in South Korea

Bruce A Mungall  1 , Hyungwoo Kim  1 , Kyu-Bin Oh  2
Affiliations

A systematic review of the burden of pertussis in South Korea

Bruce A Mungall et al. Hum Vaccin Immunother. .

Abstract

This review summarizes the published data on epidemiology and burden of pertussis in South Korea as these may be under-categorized. A systematic literature review of PubMed, SCOPUS, EMBASE and KMBASE was performed to identify published literature in South Korea since 2000. Pertussis detection rates among 19 eligible studies range from 0.7% to 100% across different age groups, detection methods and study settings. Highest rates are observed in infants, while adolescents and adults with pertussis infection may suffer from persistent coughing. Vaccination uptake of pertussis booster dose among adolescents and adults remains low while seropositivity (detection of anti-pertussis immunoglobulin G), is high among adults. This review reveals a high burden of vaccine-preventable pertussis in South Korea. Besides primary childhood vaccination, strategies like maternal immunization and decennial revaccination of adults should be considered. Active testing, reporting and better utilization of vaccine registries may provide insights for decision-makers nationwide.

Keywords: Korea; Pertussis; epidemiology; immunization; review; seropositivity; seroprevalence; vaccine.

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Graphical abstract
Figure 1.
Figure 1.
PRISMA flow diagram
Figure 2.
Figure 2.
Study characteristics. (a) Study period, (b) study setting, (c) study population, (d) baseline health status, and (e) diagnostic method
See this image and copyright information in PMC

References

    1. CDC . Epidemiology and prevention of vaccine-preventable diseases. Washington D.C., US, Public Health Foundation: National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention; 2015.
    1. European Centre for Disease Prevention and Control . Expert consultation on pertussis. Accessed 2020 June10.https://www.ecdc.europa.eu/en/publications-data/expert-consultation-pert...
    1. WHO . Pertussis vaccines: WHO position paper – august 2015. Wkly Epidemiol Rec. 2015:35.
    1. Jackson DW, Rohani P.. Perplexities of pertussis: recent global epidemiological trends and their potential causes. Epidemiol Infect. 2014;142:672–84. doi:10.1017/S0950268812003093. - DOI - PMC - PubMed
    1. Libster R, Edwards KM. Re-emergence of pertussis: what are the solutions? Expert Rev Vaccines. 2012;11:1331–46. doi:10.1586/erv.12.118. - DOI - PubMed

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