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Comment
. 2021 Jan;53(1):9-10.
doi: 10.1038/s41588-020-00758-y.

Exploiting KRAS-mediated metabolic reprogramming as a therapeutic target

Sanne Bootsma #  1   2 , Sanne M van Neerven #  1   2 , Louis Vermeulen  3   4
Affiliations
Comment

Exploiting KRAS-mediated metabolic reprogramming as a therapeutic target

Sanne Bootsma et al. Nat Genet. 2021 Jan.
No abstract available

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Comment on

  • The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
    Najumudeen AK, Ceteci F, Fey SK, Hamm G, Steven RT, Hall H, Nikula CJ, Dexter A, Murta T, Race AM, Sumpton D, Vlahov N, Gay DM, Knight JRP, Jackstadt R, Leach JDG, Ridgway RA, Johnson ER, Nixon C, Hedley A, Gilroy K, Clark W, Malla SB, Dunne PD, Rodriguez-Blanco G, Critchlow SE, Mrowinska A, Malviya G, Solovyev D, Brown G, Lewis DY, Mackay GM, Strathdee D, Tardito S, Gottlieb E; CRUK Rosetta Grand Challenge Consortium; Takats Z, Barry ST, Goodwin RJA, Bunch J, Bushell M, Campbell AD, Sansom OJ. Najumudeen AK, et al. Nat Genet. 2021 Jan;53(1):16-26. doi: 10.1038/s41588-020-00753-3. Epub 2021 Jan 7. Nat Genet. 2021. PMID: 33414552

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