Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Dec 22:11:633686.
doi: 10.3389/fimmu.2020.633686. eCollection 2020.

Editorial: The Role of Inhibitory Receptors in Inflammation and Cancer

Affiliations
Editorial

Editorial: The Role of Inhibitory Receptors in Inflammation and Cancer

Ali A Zarrin et al. Front Immunol. .
No abstract available

Keywords: ITAM; ITIM; cancer; immunoreceptor tyrosine-based inhibitory motif; inflammatory disease; inhibitory receptor.

PubMed Disclaimer

Conflict of interest statement

AZ was employed by TRexBio. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Comment on

  • Editorial on the Research Topic The Role of Inhibitory Receptors in Inflammation and Cancer

References

    1. Rumpret M, Drylewicz J, Ackermans LJE, Borghans JAM, Medzhitov R, Meyaard L. Functional categories of immune inhibitory receptors. Nat Rev Immunol (2020) 20:771–80. 10.1038/s41577-020-0352-z - DOI - PubMed
    1. Sun Y, Senger K, Baginski TK, Mazloom A, Chinn Y, Pantua H, et al. Evolutionarily conserved paired immunoglobulin-like receptor alpha (PILRalpha) domain mediates its interaction with diverse sialylated ligands. J Biol Chem (2012) 287(19):15837–50. 10.1074/jbc.M111.286633 - DOI - PMC - PubMed
    1. Sun Y, Caplazi P, Zhang J, Mazloom A, Kummerfeld S, Quinones G, et al. PILRalpha negatively regulates mouse inflammatory arthritis. J Immunol (2014) 193(2):860–70. 10.4049/jimmunol.1400045 - DOI - PubMed
    1. Rathore N, Ramani SR, Pantua H, Pantua J, Bhangale T, Wuster A, et al. Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer’s disease. PloS Genet (2018) 14(11):e1007427. 10.1371/journal.pgen.1007427 - DOI - PMC - PubMed
    1. Ravetch JV, Lanier LL. Immune inhibitory receptors. Science (2000) 290(5489):84–9. 10.1126/science.290.5489.84 - DOI - PubMed

Publication types

Substances