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. 2020 Dec 22:10:593192.
doi: 10.3389/fonc.2020.593192. eCollection 2020.

Canadian Pediatric Neuro-Oncology Standards of Practice

Julie Bennett  1 , Craig Erker  2 , Lucie Lafay-Cousin  3 , Vijay Ramaswamy  1 , Juliette Hukin  4 , Magimairajan I Vanan  5 , Sylvia Cheng  4 , Hallie Coltin  6 , Adriana Fonseca  1 , Donna Johnston  6 , Andrea Lo  7 , Shayna Zelcer  8 , Saima Alvi  9 , Lynette Bowes  10 , Josée Brossard  11 , Janie Charlebois  11 , David Eisenstat  12 , Kathleen Felton  13 , Adam Fleming  14 , Nada Jabado  15 , Valérie Larouche  16 , Geneviève Legault  15 , Chris Mpofu  13 , Sébastien Perreault  17 , Mariana Silva  18 , Roona Sinha  13 , Doug Strother  3 , Derek S Tsang  19 , Beverly Wilson  12 , Bruce Crooks  2 , Ute Bartels  1
Affiliations

Canadian Pediatric Neuro-Oncology Standards of Practice

Julie Bennett et al. Front Oncol. .

Abstract

Primary CNS tumors are the leading cause of cancer-related death in pediatrics. It is essential to understand treatment trends to interpret national survival data. In Canada, children with CNS tumors are treated at one of 16 tertiary care centers. We surveyed pediatric neuro-oncologists to create a national standard of practice to be used in the absence of a clinical trial for seven of the most prevalent brain tumors in children. This allowed description of practice across the country, along with a consensus. This had a multitude of benefits, including understanding practice patterns, allowing for a basis to compare in future research and informing Health Canada of the current management of patients. This also allows all children in Canada to receive equivalent care, regardless of location.

Keywords: ependymoma; high grade glioma; low grade glioma; medulloblastoma; national strategy; pediatric neuro-oncology; standards.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer SL declared a past co-authorship with the authors to the handling Editor.

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