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. 2021 May;45(5):1191-1197.
doi: 10.1007/s00264-020-04927-w. Epub 2021 Jan 8.

A new computed tomography scoring system to assess osteochondral allograft transplantation for the knee: inter-observer and intra-observer agreement

Pablo Eduardo Gelber  1   2 , Eduard Ramírez-Bermejo  3 , Alex Grau-Blanes  3 , Aránzazu Gonzalez-Osuna  3 , Jaume Llauger  4 , Oscar Fariñas  5
Affiliations

A new computed tomography scoring system to assess osteochondral allograft transplantation for the knee: inter-observer and intra-observer agreement

Pablo Eduardo Gelber et al. Int Orthop. 2021 May.

Abstract

Aim of the study: To describe a new semiquantitative computed tomography (CT) scoring system for multi-feature analysis of cartilage defect repair by osteochondral allografts for the knee and to assess its intra-observer and inter-observer variability.

Method: A semiquantitative assessment CT osteochondral allograft (ACTOCA) scoring system was designed based on fresh osteochondral allograft transplantations for the knee. The system includes five CT features: density relative to host bone, integration at the host-graft junction, surface percentage with a discernible cleft at the host-graft junction, cystic changes, and intra-articular fragments. Inter-observer variability was calculated by three observers blinded to the patient's medical history and treatment. Intra-observer variability was also determined.

Results: Inter-observer agreement was moderate to substantial for all CT score components and intra-observer agreement was moderate to almost perfect for all CT score components (κ > 0.5, p < 0.05).

Conclusion: The ACTOCA score is a reliable tool to evaluate integration of osteochondral allograft transplantations. It provides an accurate evaluation of bone changes and may help to standardize CT scan reports following osteochondral allograft transplantation for the knee.

Keywords: CT scoring system; Cartilage repair; Fresh OCA; Osteochondral allograft; Transplantation.

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