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Case Reports
. 2021 Sep 1;41(3):e351-e353.
doi: 10.1097/WNO.0000000000001163.

Postinfectious Optic Neuritis After Hand-Foot-Mouth Disease

Affiliations
Case Reports

Postinfectious Optic Neuritis After Hand-Foot-Mouth Disease

Spencer C Barrett et al. J Neuroophthalmol. .

Abstract

A 33-year-old man presented with acute painless loss of vision in his right eye after hand-foot-mouth disease (HFMD). Examination confirmed a right optic neuropathy. Neuroimaging and routine evaluations for alternative causes for an optic neuropathy were negative. He was treated with high dose corticosteroids and made an almost complete visual recovery. Postinfectious optic neuritis has been reported after a vast array of infections including: varicella zoster virus, influenza virus, herpes simplex virus, Epstein-Barr Virus, Lyme disease, and many others. Although Coxsackie virus infections are a known cause of HFMD and have been reported to cause maculopathy, to the best of our knowledge, this is the first reported case of optic neuritis after HFMD in the English language ophthalmic literature.

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Conflict of interest statement

The authors report no conflicts of interest.

References

    1. Kumar R, Bhargava A, Jaiswal G, Soni VR, Katbamna B, Vashisht A. A case of post encephalitic optic neuritis: clinical spectrum, differential diagnosis and management. J Ophthalmic Vis Res. 2018;13:191–194.
    1. Choi DD, Park MS, Park KA. Incidence of optic neuritis in Korean children and adolescents: a nationwide survey and national registry analysis. J Neurol Sci. 2020;408:116554.
    1. Povaliaeva DA, Egorov VV, Smoliakova GP, Danilova LP, Emanova LP, Zhajvoronok NS. Herpesviral infection as an etiological factor of acute idiopathic optic neuritis [in Russian]. Vestn Oftalmol. 2019;135:4–11.
    1. Abel A, Mcclelland C, Lee MS. Critical review: typical and atypical optic neuritis. Surv Ophthalmol. 2019;64:770–779.
    1. Nakamura M, Iwasaki Y, Takahashi T, Kaneko K, Nakashima I, Kunieda T, Kaneko S, Kusaka H. A case of MOG antibody-positive bilateral optic neuritis and meningoganglionitis following a genital herpes simplex virus infection. Mult Scler Relat Disord. 2017;17:148–150.

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