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. 2020 Dec;70(6):490-496.
doi: 10.1007/s13224-020-01331-7. Epub 2020 Aug 19.

C-Reactive Protein, Fibrinogen, Leptin, and Adiponectin Levels in Women with Polycystic Ovary Syndrome

Cagdas Ozgokce  1 , Erkan Elci  2 , Recep Yildizhan  3
Affiliations

C-Reactive Protein, Fibrinogen, Leptin, and Adiponectin Levels in Women with Polycystic Ovary Syndrome

Cagdas Ozgokce et al. J Obstet Gynaecol India. 2020 Dec.

Abstract

Background and aim: We aimed to compare the levels of clinical, biochemical, hormonal, and metabolic parameters as well as serum CRP, fibrinogen, leptin, and adiponectin in cases with PCOS and control group to investigate whether they play a role in the etiology of the syndrome.

Materials and methods: The present study included a total of 90 subjects, 45 subjects were diagnosed with PCOS (n = 45) and 45 subjects served as control group (n = 45). Serum CRP, fibrinogen, leptin, and adiponectin levels were analyzed for each subject.

Results: Serum CRP, fibrinogen, and leptin were found to be higher (statistically significant) in the group with PCOS as compared to the control group (p < 0.05). Serum Adiponectin was higher in the control group (statistically significantly) as compared with the patients in the PCOS group (p < 0.05).

Conclusion: CRP and fibrinogen (cardiac risk factor markers) increase in women with PCOS. The levels of leptin which affects metabolism increase, whereas the levels of adiponectin decrease.

Keywords: Adiponectin; CRP; Fibrinogen; Leptin; PCOS.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

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