Menopausal Hormone Therapy and Health Outcomes: Is Timing Everything?

JoAnn E Manson^{1

2}

Affiliations

¹ Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
² Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

JoAnn E Manson. Clin Chem. 2021.

. 2021 Jan 8;67(1):317-318.

doi: 10.1093/clinchem/hvaa286.

JoAnn E Manson^{1

2}

¹ Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
² Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

No abstract available

Cited by

Associations between hormone therapy use and tau accumulation in brain regions vulnerable to Alzheimer's disease.
Coughlan GT, Rubinstein Z, Klinger H, Lopez KA, Hsieh S, Boyle R, Seto M, Townsend D, Mayblyum D, Thibault E, Jacobs HIL, Farrell M, Rabin JS, Papp K, Amariglio R, Baker S, Lois C, Rentz D, Price J, Schultz A, Properzi M, Johnson K, Sperling R, Buckley RF. Coughlan GT, et al. Sci Adv. 2025 Mar 7;11(10):eadt1288. doi: 10.1126/sciadv.adt1288. Epub 2025 Mar 5. Sci Adv. 2025. PMID: 40043125 Free PMC article.

1. Manson JE, Bassuk SS.. Menopause and menopausal hormone therapy In: Jameson JL, Fauci AS, Kasper DL, Hauser S, Longo DL, Loscalzo J, editors. Harrison's Principles of Internal Medicine. 20th Ed.New York: McGraw-Hill; 2018.
1. Manson JE, Bassuk SS, Kaunitz AM, Pinkerton JV.. The Women's Health Initiative trials of menopausal hormone therapy: lessons learned. Menopause 2020;27:918–28. - PubMed
1. NAMS Hormone Therapy Position Statement Advisory Panel. The 2017 hormone therapy position statement of The North American Menopause Society. Menopause 2017;24:728–53. - PubMed
1. American College of Physicians. Guidelines for counseling postmenopausal women about preventive hormone therapy. Ann Intern Med 1992;117:1038–41. - PubMed
1. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321–33. - PubMed